1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

The discovery of the dual origin of vitamin D either by synthesis in the skin from 7-
dehydrocholesterol under the influence of UVB sunlight or from dietary origin quickly …

The vitamin D receptor (VDR) mediates virtually all of the known biological actions of the
hormonal ligand 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3). These actions are directed …

Virtually all of the known biological actions of the hormonal ligand 1, 25-dihydroxyvitamin D
3 (1, 25 (OH) 2 D 3) are mediated by the vitamin D receptor (VDR). Following binding and …

The biologically active metabolite of vitamin D, 1, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3)
is a secosteroid whose genomic mechanism of action is similar to that of other steroid …

The biologically active metabolite of vitamin D (cholecalciferol), ie 1, 25-dihydroxyvitamin D3
[1, 25 (OH) 2D3], is a secosteroid hormone whose mode of action involves stereospecific …

The conformationally flexible secosteroid, 1α, 25 (OH) 2vitamin D3 (1α, 25 (OH) 2D3)
initiates biological responses via binding to the vitamin D receptor (VDR). The VDR contains …

Recent studies have identified a heterodimer of the vitamin D receptor (VDR) and the
retinoid X receptor (RXR) as the active complex for mediating positive transcriptional effects …

Vitamin D plays a major role in bone mineral homeostasis by promoting the transport of
calcium and phosphate to ensure that the blood levels of these ions are sufficient for the …

The vitamin D receptor (VDR), the high affinity receptor for 1α, 25-dihydroxyvitamin D3 (1a,
25 (OH) 2 D 3), is a member of the nuclear receptor superfamily. VDR preferentially forms a …