Applications of decellularized extracellular matrix in bone and cartilage tissue engineering

YS Kim, M Majid, AJ Melchiorri… - … & translational medicine, 2019 - Wiley Online Library
Regenerative therapies for bone and cartilage injuries are currently unable to replicate the
complex microenvironment of native tissue. There are many tissue engineering approaches …

Functionality of decellularized matrix in cartilage regeneration: a comparison of tissue versus cell sources

Y Sun, L Yan, S Chen, M Pei - Acta biomaterialia, 2018 - Elsevier
Increasing evidence indicates that decellularized extracellular matrices (dECMs) derived
from cartilage tissues (T-dECMs) or chondrocytes/stem cells (C-dECMs) can support …

Extracellular matrix scaffolds for cartilage and bone regeneration

KEM Benders, PR Van Weeren, SF Badylak… - Trends in …, 2013 - cell.com
Regenerative medicine approaches based on decellularized extracellular matrix (ECM)
scaffolds and tissues are rapidly expanding. The rationale for using ECM as a natural …

[HTML][HTML] Preparation and use of decellularized extracellular matrix for tissue engineering

AD McInnes, MAJ Moser, X Chen - Journal of functional biomaterials, 2022 - mdpi.com
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

[HTML][HTML] Application of decellularized bone matrix as a bioscaffold in bone tissue engineering

H Amirazad, M Dadashpour, N Zarghami - Journal of biological …, 2022 - Springer
Autologous bone grafts are commonly used as the gold standard to repair and regenerate
diseased bones. However, they are strongly associated with postoperative complications …

[HTML][HTML] Functional acellular matrix for tissue repair

B Wang, T Qinglai, Q Yang, M Li, S Zeng, X Yang… - Materials Today Bio, 2023 - Elsevier
In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

A review of decellularized extracellular matrix biomaterials for regenerative engineering applications

DE Heath - Regenerative Engineering and Translational Medicine, 2019 - Springer
Biomaterials are a cornerstone technology of the biomedical device, tissue engineering, and
regenerative medicine industries. While traditional biomaterials are fully defined synthetics …

Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering

CW Cheng, LD Solorio, E Alsberg - Biotechnology advances, 2014 - Elsevier
The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Controlling stem cell behavior with decellularized extracellular matrix scaffolds

G Agmon, KL Christman - Current Opinion in Solid State and Materials …, 2016 - Elsevier
Decellularized tissues have become a common regenerative medicine platform with multiple
materials being researched in academic laboratories, tested in animal studies, and used …