Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …

3500 Background: Mounting evidence indicates an enhanced lymphocytic reaction as an
informative prognostic indicator in colon cancer (CC). The IM methodology has been defined …

PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …

Background New and fully validated tests need to be brought into clinical practice to improve
the estimation of recurrence risk in patients with colon cancer. The aim of this study was to …

Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) tumor, nodes, metastasis (TNM) classification system based on tumor features …

Abstract Background The American Joint Committee on Cancer staging and other
prognostic tools fail to account for stage-independent variability in outcome. We developed a …

There is growing evidence that the immune system may prevent the occurrence, growth and
metastatic diffusion of colorectal cancer (CRC). The role played by the adaptive immune …

Current cancer classification is based on intrinsic tumor parameters such as characteristic of
tumor cells, tumor progression, tumor invasion and the presence of distant metastases, as …

Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine …

Tumors evolve in close interaction with their microenvironment, which encompasses a
continual tension between the developing tumor and the host immune system. Clinical trials …