A study on co-modification of MSNs with some transition metals and polyethyleneimine (PEI) as a versatile strategy for efficient delivery of short oligonucleotides
R Badihi, A Mahmoudi, MR Sazegar, K Nazari - Chemical Papers, 2022 - Springer
In this research, mesoporous silica nanoparticles (MSNs) were synthesized and
hydrothermally modified with different transition metals, including Co2+, Fe2+, and Zn2+ …
hydrothermally modified with different transition metals, including Co2+, Fe2+, and Zn2+ …
[HTML][HTML] Synthesis of nanocomposites based on mesoporous aluminosilicate and polyethyleneimine (PEI) for sirna delivery: potential usefulness of the synergistic …
R Badihi, A Mahmoudi, MR Sazegar… - Journal of …, 2021 - fortunepublish.com
Several nanocomposites based on Mesoporous Silica Nanoparticles (MSN), aluminum ions,
and Polyethyleneimine (PEI) were synthesized by the combination of the sol-gel and post …
and Polyethyleneimine (PEI) were synthesized by the combination of the sol-gel and post …
[HTML][HTML] Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
Gene therapy using siRNA molecules is nowadays considered as a promising approach.
For successful therapy, development of a stable and reliable vector for siRNA is crucial. Non …
For successful therapy, development of a stable and reliable vector for siRNA is crucial. Non …
Enhanced gene delivery by polyethyleneimine coated mesoporous silica nanoparticles
H Zarei, R Kazemi Oskuee… - Pharmaceutical …, 2019 - Taylor & Francis
Due to large surface area, tunable pore size, easy surface manipulation, and low-toxicity
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …
The packaging of siRNA within the mesoporous structure of silica nanoparticles
Mesoporous silica nanoparticle (MSN) is a promising material for biomedical applications,
such as delivering drugs or biological molecules (siRNA or DNA), to the target cells or …
such as delivering drugs or biological molecules (siRNA or DNA), to the target cells or …
[PDF][PDF] Synthesis and Characterization of Silk Fibroin-Coated Mesoporous Silica Nanoparticles for Tioguanine Targeting to Leukemia.
Mesoporous silica nanoparticles (MSNs) are known as carriers with high loading capacity
and large functionalizable surface area for target-directed delivery. In this work, large pore …
and large functionalizable surface area for target-directed delivery. In this work, large pore …
Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine
SR Bhattarai, E Muthuswamy, A Wani… - Pharmaceutical …, 2010 - Springer
Purpose To prepare mesoporous silica-based delivery systems capable of simultaneous
delivery of drugs and nucleic acids. Methods The surface of mesoporous silica nanoparticles …
delivery of drugs and nucleic acids. Methods The surface of mesoporous silica nanoparticles …
Mesoporous silica nanoparticles for enhancing the delivery efficiency of immunostimulatory DNA drugs
C Tao, Y Zhu, Y Xu, M Zhu, H Morita… - Dalton Transactions, 2014 - pubs.rsc.org
We developed a potential immunostimulatory double-stranded DNA (dsDNA) delivery
system by the binding of dsDNA to amino-modified mesoporous silica nanoparticles (MSNs) …
system by the binding of dsDNA to amino-modified mesoporous silica nanoparticles (MSNs) …
Proper functional modification and optimized adsorption conditions improved the DNA loading capacity of mesoporous silica nanoparticles
B Niu, Y Zhou, T Wen, G Quan, V Singh, X Pan… - Colloids and Surfaces A …, 2018 - Elsevier
Packaging enough genetic materials is necessary for gene delivery, but functional
modification of the carriers may affect their gene loading capacity. In this study, RGD peptide …
modification of the carriers may affect their gene loading capacity. In this study, RGD peptide …
Adsorption and protection of plasmid DNA on mesoporous silica nanoparticles modified with various amounts of organosilane
H Yang, K Zheng, Z Zhang, W Shi, S Jing… - Journal of colloid and …, 2012 - Elsevier
Ordered MCM-41-type mesoporous silica nanoparticles (MSNs) with pore size of 2.6 nm
were synthesized and were further modified with various amounts of 3 …
were synthesized and were further modified with various amounts of 3 …