Acute kidney injury biomarkers: Are we ready for the biomarker curve?

C Ronco - Cardiorenal Medicine, 2019 - karger.com
Acute kidney injury (AKI) is common in critically ill patients and carries severe complications
and a high risk of mortality [1]. Consequently, all preventive and protective strategies should …

Update on biomarkers of acute kidney injury: moving closer to clinical impact?

H Schiffl, SM Lang - Molecular diagnosis & therapy, 2012 - Springer
Acute kidney injury (AKI) represents a common disorder in hospitalized patients, and its
incidence is rising at an alarming rate. Despite significant improvements in critical care and …

Have biomarkers failed in acute kidney injury? No

BA McMahon, JL Koyner - Intensive Care Medicine, 2017 - Springer
Over the past decade, large prospective cohort studies have repeatedly shown that novel
biomarkers are superior in performance to serum creatinine (SCr) in the early diagnosis and …

Biomarkers of acute kidney injury: can we replace serum creatinine?

P Dennen, CR Parikh - Clinical nephrology, 2007 - europepmc.org
Acute kidney injury (AKI) is frequent in hospitalized critically ill patients and mortality
associated with AKI is largely unchanged over many decades. The new nomenclature, AKI …

Use of biomarkers to assess prognosis and guide management of patients with acute kidney injury

DN Cruz, SM Bagshaw, A Maisel… - ADQI Consensus on …, 2013 - karger.com
Several new biomarkers of kidney damage have been characterized and are being
validated in clinical studies. These damage biomarkers complement existing conventional …

Biomarkers for AKI improve clinical practice: no

M Ostermann, M Joannidis - Intensive care medicine, 2015 - Springer
Despite recent developments in definition and staging, the diagnosis of (AKI) acute kidney
injury is still based on oliguria and/or an increase in serum creatinine [1]. Consequently …

Biomarkers for AKI improve clinical practice: yes

M Legrand, M Darmon - Intensive Care Medicine, 2015 - Springer
Up to 40% of critically ill patients will develop an acute kidney injury (AKI)[1]. This renal
complication is associated with high morbidity, high short-term and longterm mortality and a …

New biomarkers of acute kidney injury

CR Parikh, P Devarajan - Critical care medicine, 2008 - journals.lww.com
Acute kidney injury (AKI) represents a major clinical problem, with rising incidence and high
mortality rate. The lack of early biomarkers has resulted in a delay in initiating therapies …

Current status of novel biomarkers for the diagnosis of acute kidney injury: a historical perspective

BR Griffin, KM Gist, S Faubel - Journal of intensive care …, 2020 - journals.sagepub.com
Acute kidney injury (AKI) is a common and serious medical condition associated with
significant increases in morbidity, mortality, and cost of care. Because of the high incidence …

A long journey for acute kidney injury biomarkers

DJ Oh - Renal failure, 2020 - Taylor & Francis
Acute kidney injury (AKI) is a life-threatening illness that continues to have an in-hospital
mortality rate of patients with AKI ranges from 20% to 50% or greater, depending on …