[HTML][HTML] A decreased level of soluble klotho can predict cardiovascular death in no or mild abdominal aortic calcification hemodialysis patients

H Cai, X Zhu, J Lu, M Zhu, S Liu, Y Zhan, Z Ni… - Frontiers in …, 2021 - frontiersin.org
Background: Soluble Klotho plays an important role in cardiovascular disease and death in
chronic kidney disease (CKD). We assessed the relationship between serum soluble Klotho …

Serum soluble klotho level is associated with abdominal aortic calcification in patients on maintenance hemodialysis

H Cai, R Lu, M Zhang, H Pang, M Zhu, W Zhang… - Blood …, 2015 - karger.com
Background: Klotho is a single transmembrane protein originally identified as an 'aging
suppressor'. Emerging evidence reveals that soluble Klotho (sKl) in the circulation plays …

[HTML][HTML] The association between soluble klotho and cardiovascular parameters in chronic kidney disease: results from the KNOW-CKD study

HJ Kim, E Kang, YK Oh, YH Kim, SH Han, TH Yoo… - BMC nephrology, 2018 - Springer
Background Klotho, a protein linked to aging, has emerged as a pivotal player in mineral
bone metabolism and might explain the relationship between chronic kidney disease (CKD) …

[HTML][HTML] Association of serum klotho levels with different-staged vascular calcification status in patients with maintenance hemodialysis

Y Lin, J Huang, M Zhou, C Pan, A Shan, C Zhou - BMC nephrology, 2022 - Springer
Background Vascular calcification (VC) is suggested to be associated with serum klotho
levels in patients with maintenance hemodialysis (MHD), whereas there is a lack of reports …

[HTML][HTML] Association of soluble klotho level with adverse outcomes in patients on maintenance hemodialysis

L Yu, Q Liu, J Feng, S Li, X Gu, Y Xiong, JM Ye - Disease Markers, 2020 - hindawi.com
Background. The predictive value of soluble Klotho (sKlotho) for adverse outcomes in
patients on maintenance hemodialysis (MHD) is controversial. In this study, we aimed to …

[HTML][HTML] Soluble Klotho is associated with mortality and cardiovascular events in hemodialysis

E Memmos, P Sarafidis, P Pateinakis, A Tsiantoulas… - BMC nephrology, 2019 - Springer
Background Klotho is a transmembrane protein acting as a co-receptor for FGF-23 and thus
exerts clinical actions on mineral metabolism. The association of secreted Klotho with …

Lower circulating soluble Klotho level is associated with increased risk of all-cause mortality in chronic kidney disease patients: a systematic review and meta-analysis

N Charoenngam, B Ponvilawan… - International Urology and …, 2020 - Springer
Purpose This study aimed to investigate the association between circulating soluble Klotho
level and risk of all-cause mortality in chronic kidney disease (CKD) patients using …

The prognostic value of soluble Klotho in patients with haemodialysis: a systematic review and meta-analysis

QF Liu, SS Li, LX Yu, JH Feng… - … Advances in Chronic …, 2020 - journals.sagepub.com
Aim: The correlation between soluble Klotho (sKlotho) levels and clinical outcomes remains
inconclusive for patients undergoing maintenance haemodialysis (MHD). We aimed to …

[HTML][HTML] Relationship between serum soluble Klotho protein and coronary artery calcification and prognosis in patients on maintenance hemodialysis

S Zheng, Y Zheng, JIN Lingwei, Z Zhihong… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Background: We aimed to investigate the relationship between serum soluble Klotho protein
(sKlotho) level and coronary artery calcification (CAC) as well as prognosis in patients with …

[HTML][HTML] Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients

MS Buiten, MK de Bie, A Bouma-de Krijger, B van Dam… - BMC nephrology, 2014 - Springer
Background Dialysis patients suffer from a high burden of cardiovascular disease (CVD).
Partly this is due to progressive deterioration of calcium-phosphate homeostasis. Previous …