Dry eye syndromes can involve both nociceptive and neuropathic symptoms. Nociceptive
symptoms are the normal physiological responses to noxious stimuli. Neuropathic symptoms …

Cornea is one of the most densely innervated tissues in the body and is abundantly supplied
by different types of nerve fibers. A study in the rabbit cornea showed that the nerve density …

Dry eye is a common, multifactorial disease currently diagnosed by a combination of
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …

Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision …

Cases of dry eye disease involving a neuropathic basis for symptoms and a poor correlation
between symptoms and objective signs of dry eye disease can be associated with …

Recent data suggest that corneal somatosensory dysfunction may be the underlying cause
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …

Dry eye (DE) disease is a multifactorial, chronic condition with a prevalence of 5-41 30%. 1
DE symptoms are a frequent presenting complaint to eye clinics and can include 42 …

Objective. Dry eye is a multi-factorial disorder that manifests with painful ocular symptoms
and visual disturbances, which can only be partly attributed to tear dysfunction. This disorder …

Objective: To evaluate the association between dry eye (DE) symptoms and neuropathic-like
ocular pain (NOP) features, chronic pain conditions, depression, and anxiety in patients …

Ocular discomfort and eye pain are frequently reported by patients with dry eye disease
(DED), and their management remains a real therapeutic challenge for the Ophthalmologist …