Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

PD Lister, DJ Wolter, ND Hanson - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Treatment of infectious diseases becomes more challenging with each passing year. This is
especially true for infections caused by the opportunistic pathogen Pseudomonas …

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment

REW Hancock, DP Speert - Drug resistance updates, 2000 - Elsevier
Pseudomonas aeruginosa continues to be a major cause of infections in Western society, in
part because of its high intrinsic resistance to antibiotics. It has been demonstrated that this …

Pseudomonas Aeruginosa: Resistance to the Max

K Poole - Frontiers in microbiology, 2011 - frontiersin.org
Pseudomonas aeruginosa is intrinsically resistant to a variety of antimicrobials and can
develop resistance during anti-pseudomonal chemotherapy both of which compromise …

Pseudomonas aeruginosa: a clinical and genomics update

AC Pelegrin, M Palmieri, C Mirande… - FEMS Microbiology …, 2021 - academic.oup.com
Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Genetic markers of widespread extensively drug-resistant Pseudomonas aeruginosa high-risk clones

G Cabot, AA Ocampo-Sosa… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Recent reports have revealed the existence of widespread extensively drug-resistant (XDR)
P. aeruginosa high-risk clones in health care settings, but there is still scarce information on …

Pseudomonas aeruginosa: all roads lead to resistance

EBM Breidenstein, C de la Fuente-Núñez… - Trends in …, 2011 - cell.com
Pseudomonas aeruginosa is often resistant to multiple antibiotics and consequently has
joined the ranks of 'superbugs' due to its enormous capacity to engender resistance. It …

Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosa

A Dötsch, T Becker, C Pommerenke… - Antimicrobial agents …, 2009 - Am Soc Microbiol
The emergence of antimicrobial drug resistance is of enormous public concern due to the
increased risk of delayed treatment of infections, the increased length of hospital stays, the …

The intrinsic resistome of Pseudomonas aeruginosa to β-lactams

C Alvarez-Ortega, I Wiegand, J Olivares, REW Hancock… - Virulence, 2011 - Taylor & Francis
Pseudomonas aeruginosa is a relevant opportunistic pathogen particularly problematic due
to its low intrinsic susceptibility to antibiotics. Intrinsic resistance has been traditionally …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …