Late-onset Alzheimer's disease (AD) is the most common cause of dementia and
epidemiological studies show that type 2 diabetes (T2D) increases the risk of AD. However …

Hyperinsulinemia is a risk factor for late-onset Alzheimer's disease (AD). In vitro experiments
describe potential connections between insulin, insulin signaling, and amyloid-β (Aβ), but in …

Epidemiological studies show that patients with type 2 diabetes (T2DM) and individuals with
a diabetes-independent elevation in blood glucose have an increased risk for developing …

Many studies show that there is a link between Alzheimer's disease and type 2 diabetes.
Both disorders also share a number of pathophysiological features, including cognitive …

Background Although increasing evidence has indicated that brain insulin dysfunction is a
risk factor for Alzheimer disease (AD), the underlying mechanisms by which insulin …

Background Defects in insulin production and signalling are suspected to share a key role in
diabetes and Alzheimer's disease (AD), two age-related prevalent illnesses. Methods In this …

Background Diabetes is a risk factor for developing Alzheimer's disease (AD); however, the
mechanism by which diabetes can promote AD pathology remains unknown. Diabetes …

Defects in insulin production and signaling are suspected to share a key role in diabetes
and Alzheimer disease (AD), two age-related pathologies. In this study, we investigated the …

Although evidence is accumulating that diabetes mellitus is an important risk factor for
sporadic Alzheimer's disease (AD), the mechanisms by which defects in insulin signaling …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by beta-
amyloid (Abeta) deposition, neurofibrillary tangles and cognitive decline. Clinical data …