[HTML][HTML] Metformin and cancer: An existing drug for cancer prevention and therapy

F Zi, H Zi, Y Li, J He, Q Shi, Z Cai - Oncology letters, 2018 - spandidos-publications.com
Metformin is a standard clinical drug used to treat type 2 diabetes mellitus (T2DM) and
polycystic ovary syndrome. Recently, epidemiological studies and meta‑analyses have …

Metformin in cancer treatment and prevention

DR Morales, AD Morris - Annual review of medicine, 2015 - annualreviews.org
Patients with diabetes mellitus are at increased risk of cancer development. Metformin is a
well-established, effective agent for the management of type 2 diabetes mellitus …

[HTML][HTML] Metformin: A promising drug for human cancers

H Wu, D Huang, H Zhou, X Sima, Z Wu… - Oncology …, 2022 - spandidos-publications.com
Small‑molecule chemical drugs are of great significance for tumor‑targeted and
individualized therapies. However, the development of new small‑molecule drugs, from …

Metformin: its emerging role in oncology

D Micic, G Cvijovic, V Trajkovic, LH Duntas, S Polovina - Hormones, 2011 - Springer
Metformin is considered, in conjunction with lifestyle modification, as a first-line treatment
modality for type 2 diabetes mellitus (DM). Recently, several clinical studies have reported …

Metformin: taking away the candy for cancer?

M Jalving, JA Gietema, JD Lefrandt, S de Jong… - European journal of …, 2010 - Elsevier
Metformin is widely used in the treatment of diabetes mellitus type 2 where it reduces insulin
resistance and diabetes-related morbidity and mortality. Population-based studies show that …

Metformin: a novel but controversial drug in cancer prevention and treatment

X Sui, Y Xu, X Wang, W Han, H Pan… - Molecular …, 2015 - ACS Publications
Metformin, a biguanide derivative that is widely used for treating type 2 diabetes mellitus,
has recently been shown to exert potential anticancer effects. Many retrospective data and …

Metformin: An anti-diabetic drug to fight cancer

M Daugan, AD Wojcicki, B d'Hayer, V Boudy - Pharmacological research, 2016 - Elsevier
Since epidemiologic data have highlighted the positive effects of metformin to reduce cancer
incidence and mortality, many in vitro and in vivo studies as well as a large number of …

Metformin and cancer: new applications for an old drug

TV Kourelis, RD Siegel - Medical Oncology, 2012 - Springer
Metformin, one of most widely prescribed oral hypoglycemic agents, has recently received
increased attention because of its potential antitumorigenic effects that are thought to be …

Metformin and cancer therapy

F Bost, IB Sahra, Y Le Marchand-Brustel… - Current opinion in …, 2012 - journals.lww.com
Metformin and cancer therapy : Current Opinion in Oncology Metformin and cancer therapy :
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Investigating metformin for cancer prevention and treatment: the end of the beginning

MN Pollak - Cancer discovery, 2012 - AACR
Laboratory research and pharmacoepidemiology are providing converging evidence that
the widely used antidiabetic drug metformin has antineoplastic activity, but there are …