Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF‐κB and induction of apoptosis

P Onori, S DeMorrow, E Gaudio… - … journal of cancer, 2009 - Wiley Online Library
Caffeic acid phenethyl ester (CAPE) inhibits the growth of tumor cells and is a known
inhibitor of nuclear factor kappa beta (NF‐κB), which is constitutively active in …

[HTML][HTML] Effect of caffeic acid phenethyl ester on proliferation and apoptosis of colorectal cancer cells in vitro

D Wang, DB Xiang, YJ He, ZP Li, XH Wu… - World journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To study the effect of caffeic acid phenethyl ester (CAPE) on proliferation, cell cycle,
apoptosis and expression of β-catenin in cultured human colorectal cancer (CRC) cell line …

Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual …

TW Chung, SK Moon, YC Chang, JH Ko… - The FASEB …, 2004 - Wiley Online Library
Our previous studies have clearly shown that the angiogenic enzymes, matrix
metalloproteinase (MMP)‐2/9, are directly involved in human hepatic tumorigenesis and …

Inhibitory effect of caffeic acid phenethyl ester on the growth of C6 glioma cells in vitro and in vivo

HC Kuo, WH Kuo, YJ Lee, WL Lin, FP Chou, TH Tseng - Cancer letters, 2006 - Elsevier
Caffeic acid phenethyl ester (CAPE), a component of honeybee propolis, has been reported
to hold various biochemical responses. In the preliminary study, we found that CAPE …

Low concentration of caffeine inhibits the progression of the hepatocellular carcinoma via Akt signaling pathway

S Dong, J Kong, J Kong, Q Shen, F Kong… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
Accumulating evidences have reported that caffeine has anticancer effects at high blood
concentrations. However, whether caffeine has anticancer effects on human hepatocellular …

Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway

Y Liang, G Feng, L Wu, S Zhong, X Gao… - Drug design …, 2019 - Taylor & Francis
Purpose: Caffeic acid phenethyl ester (CAPE) is the main polyphenol extracted from
honeybee propolis, which inhibits the growth of several kinds of tumor. This study aimed to …

[HTML][HTML] Inhibitory effect of caffeic acid phenethyl ester on the growth of SW480 colorectal tumor cells involves β-catenin associated signaling pathway down-regulation

YJ He, BH Liu, DB Xiang, ZY Qiao, T Fu… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To study the anti-tumor effect of caffeic acid phenethyl ester (CAPE) and the influence
of CAPE on β-catenin associated signaling pathway in SW480 colorectal cancer (CRC) …

Caffeic acid phenethyl ester (CAPE) induced apoptosis in serous ovarian cancer OV7 cells by deregulation of BCL2/BAX genes

A Kleczka, R Kubina, R Dzik, K Jasik, J Stojko… - Molecules, 2020 - mdpi.com
Ovarian cancer has the worst prognosis among all gynecological cancers. Therefore, it
seems reasonable to seek new drugs that may improve the effectiveness of treatment or …

[HTML][HTML] Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester

YJ He, WL Li, BH Liu, H Dong, ZR Mou… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To investigate the molecular mechanisms of the anti-cancer activity of caffeic acid
phenethyl ester (CAPE). METHODS: Protein profiles of human colorectal cancer SW480 …

Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway

CL Lin, RF Chen, JYF Chen, YC Chu… - International Journal of …, 2012 - mdpi.com
Caffeic acid (CA), a natural phenolic compound, is abundant in medicinal plants. CA
possesses multiple biological effects such as anti-bacterial and anti-cancer growth. CA was …