Combinations of artemisinin and quinine for uncomplicated falciparum malaria were studied.
A total of 268 patients were randomized to 7 days of quinine at 10 mg/kg of body weight …

The efficacy of artemisinin monotherapy was studied in 227 patients with uncomplicated
falciparum malaria. They all received artemisinin at t 0 hr, t 8 hr, and thereafter once daily; …

Two oral regimens comprising a single dose of 20 mg/kg of artemisinin followed by three
days of quinine, 10 mg/kg three times a day (AQ), or doxycycline, 4 mg/kg once a day (AD) …

For the treatment of patients with acute falciparum malaria, the combination of artemisinin as
a single dose with a single dose of mefloquine was studied in 4 separate prospective trials …

The activity of artemisinin in combination with mefloquine was tested in vitro against a
chloroquine‐sensitive (F32) strain of Plasmodium falciparum. A method of repetitive dosing …

The pharmacokinetics of artemisinin was studied in 11 Vietnamese patients with
uncomplicated falciparum malaria after a single 500 mg oral dose. Curative treatment with …

To study the efficacy, tolerance, population pharmacokinetics and pharmacodynamics of
artesunate followed by mefloquine at various intervals, 360 patients with Plasmodium …

Quinine and the artemisinin-derivative drugs artesunate and artemether are effective
treatments for severe falciparum malaria. Trials comparing artemether with quinine have not …

It has been suggested recently, based on pharmacokinetic-pharmacodynamic modelling
exercises, that twice daily dosing of artemisinins increases malaria parasite killing and so …

The efficacy of the combination of a single oral dose of 500 mg artemisinin with a single 500
mg oral dose of mefloquine (AM) in the treatment of uncomplicated falciparum malaria was …