Low dose radiation therapy as a potential life saving treatment for COVID-19-induced acute respiratory distress syndrome (ARDS)

G Dhawan, R Kapoor, R Dhawan, R Singh… - Radiotherapy and …, 2020 - Elsevier
The new coronavirus COVID-19 disease caused by SARS-CoV-2 was declared a global
public health emergency by WHO on Jan 30, 2020. Despite massive efforts from various …

[HTML][HTML] Is low dose radiation therapy a potential treatment for COVID-19 pneumonia?

C Kirkby, M Mackenzie - Radiotherapy and Oncology, 2020 - ncbi.nlm.nih.gov
Fatal cases of COVID-19 are characterised by acute respiratory distress syndrome (ARDS),
sepsis, pneumonia and respiratory failure [1]. The high transmission rate of the virus and the …

Low-dose radiation therapy in the management of coronavirus disease 2019 (COVID-19) pneumonia (LOWRAD-Cov19): Preliminary report

N Sanmamed, P Alcantara, E Cerezo… - International Journal of …, 2021 - Elsevier
Purpose Low-dose radiation therapy (LD-RT) has been shown to have an anti-inflammatory
effect, and preliminary results suggest it is feasible to treat patients with coronavirus disease …

Low-dose radiation therapy (LDRT) for COVID-19: Benefits or risks?

PG Prasanna, GE Woloschak, AL DiCarlo… - Radiation …, 2020 - meridian.allenpress.com
The limited impact of treatments for COVID-19 has stimulated several phase 1 clinical trials
of whole-lung low-dose radiation therapy (LDRT; 0.3–1.5 Gy) that are now progressing to …

Nrf2 activation putatively mediates clinical benefits of low-dose radiotherapy in COVID-19 pneumonia and acute respiratory distress syndrome (ARDS): Novel …

EJ Calabrese, WJ Kozumbo, R Kapoor… - Radiotherapy and …, 2021 - Elsevier
Novel mechanistic insights are discussed herein that link a single, nontoxic, low-dose
radiotherapy (LDRT) treatment (0.5–1.0 Gy) to (1) beneficial subcellular effects mediated by …

[HTML][HTML] Low dose lung radiotherapy for COVID-19 pneumonia. The rationale for a cost-effective anti-inflammatory treatment

PC Lara, J Burgos, D Macias - Clinical and Translational Radiation …, 2020 - Elsevier
The COVID-19 pandemia is affecting people worldwide. Most of the patients suffered of a
respiratory disease that will progress to an acute respiratory distress syndrome (ARDS) …

Low-dose radiation therapy for COVID-19 pneumonia: a pilot study

DN Sharma, R Guleria, N Wig, A Mohan… - The British journal of …, 2021 - academic.oup.com
Objectives: The World Health Organization (WHO) has declared coronavirus disease 2019
(COVID-19) as pandemic in March 2020. Currently there is no specific effective treatment for …

Lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable

DG Kirsch, M Diehn, FA Cucinotta… - Radiotherapy and …, 2020 - thegreenjournal.com
The novel coronavirus SARS-CoV-2 is causing an ongoing pandemic of COVID-19 that has
killed over 200,000 people in countries around the world. Infection with this single-stranded …

Immunomodulatory low-dose whole-lung radiation for patients with coronavirus disease 2019-related pneumonia

CB Hess, TH Nasti, VR Dhere, TJ Kleber… - International Journal of …, 2021 - Elsevier
Purpose Phase 1 clinical trials have established low-dose, whole-lung radiation therapy (LD-
RT) as safe for patients with coronavirus disease 2019 (COVID-19)-related pneumonia. By …

[HTML][HTML] Could pulmonary low-dose radiation therapy be an alternative treatment for patients with COVID-19 pneumonia? Preliminary results of a multicenter SEOR …

M Arenas, M Algara, G De Febrer, C Rubio… - Strahlentherapie und …, 2021 - Springer
Purpose To evaluate the efficacy and safety of lung low-dose radiation therapy (LD-RT) for
pneumonia in patients with coronavirus disease 2019 (COVID-19). Materials and methods …