Background Pseudomonas aeruginosa is an opportunistic pathogen consisting of three
phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific …

In this chapter, we leverage a novel approach to assess the seamless population structure of
Pseudomonas aeruginosa, using the full repertoire of genomes sequenced to date …

The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …

Extensive use of next-generation sequencing has the potential to transform our knowledge
on how genomic variation within bacterial species impacts phenotypic versatility. Because …

Background Drug treatments and vaccine designs against the opportunistic human
pathogen Pseudomonas aeruginosa have multiple issues, all associated with the diverse …

Background The constant increase in development and spread of bacterial resistance to
antibiotics poses a serious threat to human health. New sequencing technologies are now …

The first Pseudomonas genome was sequenced in 2000, and at 6.3 million base pairs, it
was, at the time, the largest bacterial genome ever sequenced (Stover et al., 2000). Not …

The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …

Background Pseudomonas aeruginosa is an opportunistic pathogen with a high incidence
of hospital infections that represents a threat to immune compromised patients. Genomic …

Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide range of acute
and chronic infections. An increasing number of isolates have mutations that make them …