With the pandemic of severe acute respiratory syndrome coronavirus 2, vaccine delivery
systems emerged as a core technology for global public health. Given that antigen …

Vaccination is one of the most successful and cost‐effective prophylactic measures against
diseases, especially infectious diseases including smallpox and polio. However, the …

Researchers working on the development of vaccines face an inherent dilemma: to
maximize immunogenicity without compromising safety and tolerability. Early vaccines often …

An appropriate delivery system can improve the immune effects of antigens against various
infections or tumors. Antigen-presenting cells (APCs) are specialized to capture and process …

Vaccines represent the most relevant contribution of immunology to human health. However,
despite the remarkable success achieved in the past years, many vaccines are still missing …

RNA-based therapeutics have shown great promise in various medical applications,
including cancers, infectious diseases, and metabolic diseases. The recent success of …

The deployment of molecular to microscale carriers for intracellular delivery has tremendous
potential for biology and medicine, especially for in vivo therapies. The field remains limited …

The ideal vaccine is a simple and stable formulation which can be conveniently
administered and provides life-long immunity against a given pathogen. The development of …

Subunit vaccines offer a safer alternative to traditional organism-based vaccines, but their
immunogenicity is impaired. This hurdle might be overcome by the use of micro-and …

Viruses can be engineered to efficiently deliver exogenous genes, but their natural gene
delivery properties often fail to meet human therapeutic needs. Therefore, engineering viral …