Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …

The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

Gene therapy has attracted much attention in modern society and provides a promising
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …

Silica nanoparticles (SNPs) have attracted widespread attention as biocompatible and
efficient nanocarriers for gene delivery. The physicochemical properties of SNPs such as …

We have known for a while that silica is a promising candidate gene delivery vector. New in
vivo data from Dhruba Bharali and co-workers raise the hopes a notch for such approaches …

Finding and exploiting safe and high-efficiency gene carriers have always been critical tasks
for gene therapy. In this work, novel GSH-triggered degradable organosilica nanoparticles …

Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …

In order to develop a safe and effective gene therapy carrier, some toxicological and
biodynamical experiments were carried out on silica nanoparticles (SiNPs). First we …

Uniform-sized amino-modified silica nanoparticles have been prepared by the controlled
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …