In this study, we provide the first comprehensive annotation of the entire family of canine
interferons (IFNs). Canine IFN-ɛ (IFNE), IFN-κ (IFNK), and IFN-λ (IFNL) were discovered for …

In this study, we provide the first comprehensive annotation of canine interferon-λ (CaIFN-λ,
type III IFN). Phylogenetic analysis based on genomic sequences indicated that CaIFN-λ is …

Interferon (IFN) is thought to play an important role in the vertebrate immune system, but
systemic knowledge of IFN evolution has yet to be elucidated. To evaluate the phylogenic …

The interferons (IFNs) are a large family of multifunctional secreted protein involved in
antiviral defense, cell growth regulation, and immune activation. The human IFNs are used …

Interferons (IFN) provide a critical first line of defense against viral infection in vertebrates.
Moreover, IFN-λ, a recently identified group of mammalian IFN, has demonstrated antiviral …

Interferon-δ (IFN-δ) belongs to type I IFN. It was first identified by Lefevre in 1993. The
porcine interferon-δ (PoIFN-δ)–related sequences were reported in 2009. The IFN-δ-related …

Recently, an original research discovers a new type of interferon (IFN) system in jawed
vertebrates, including type IV IFN (IFN-υ or IFNU) and its receptors (IFN-υR1 and IL-10R2) …

A bovine IFN-ε (BoIFN-ε) gene was amplified from bovine liver genomic DNA consisting of a
463 bp partial 5′ UTR, 582 bp complete ORF and 171 bp partial 3′ UTR, which encodes a …

Type III interferons (IFNLs) have critical roles in the host's innate immune system, also
serving as the first line against pathogenic infections of mucosal surfaces. In mammals …

Abstract Interferon-epsilon (IFN-ε) is a type I IFN playing an essential role in innate and
adaptive immunity against viral infection. Ovis aries IFN-ε (OvIFN-ε), consisting of 582 bp …