Salt sensitivity: challenging and controversial phenotype of primary hypertension

R Iatrino, P Manunta, L Zagato - Current hypertension reports, 2016 - Springer
Increases in life expectancy and cardiovascular adverse events in patients with
hypertension highlight the need for new risk-reduction strategies to reduce the burden of …

[HTML][HTML] Pathophysiology and genetics of salt-sensitive hypertension

D Maaliki, MM Itani, HA Itani - Frontiers in Physiology, 2022 - frontiersin.org
Most hypertensive cases are primary and heavily associated with modifiable risk factors like
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …

[PDF][PDF] Salt sensitivity and hypertension: a paradigm shift from kidney malfunction to vascular endothelial dysfunction

HY Choi, HC Park, SK Ha - … & Blood Pressure: E & BP, 2015 - synapse.koreamed.org
Hypertension is a complex trait determined by both genetic and environmental factors and is
a major public health problem due to its high prevalence and concomitant increase in the …

Genetics of salt-sensitive hypertension

H Sanada, JE Jones, PA Jose - Current hypertension reports, 2011 - Springer
The assessment of salt sensitivity of blood pressure is difficult because of the lack of
universal consensus on definition. Regardless of the variability in the definition of salt …

Evaluation of the pathophysiological mechanisms of salt-sensitive hypertension

D Hirohama, T Fujita - Hypertension Research, 2019 - nature.com
The currently available data have indicated that dietary salt is directly correlated with blood
pressure (BP) and the occurrence of hypertension. However, the salt sensitivity of BP is …

Genomics and pharmacogenomics of salt-sensitive hypertension

I Armando, AM Van Villar… - Current hypertension …, 2015 - ingentaconnect.com
Salt sensitivity is estimated to be present in 51% of the hypertensive and 26% of the
normotensive populations. The individual blood pressure response to salt is heterogeneous …

Genomic epidemiology of blood pressure salt sensitivity

TN Kelly, J He - Journal of hypertension, 2012 - journals.lww.com
High blood pressure (BP) is a complex trait determined by genetic and environmental
factors, as well as their interactions. Over the past few decades, there has been substantial …

Genetics of salt-sensitive hypertension

P Strazzullo, F Galletti - Current hypertension reports, 2007 - Springer
Excess dietary salt intake represents a predominant cause of hypertension. However,
individual blood pressure response to salt is heterogeneous, possibly due to different …

Mechanisms of salt-sensitive hypertension

L Luzardo, O Noboa, J Boggia - Current hypertension reviews, 2015 - ingentaconnect.com
Hypertension and its consequences, including heart failure, stroke, and kidney disease, are
responsible for substantial morbidity and mortality worldwide. Lifestyle changes, particularly …

Salt-sensitive hypertension: mechanisms and effects of dietary and other lifestyle factors

L Pilic, CR Pedlar, Y Mavrommatis - Nutrition reviews, 2016 - academic.oup.com
Salt sensitivity, which is an increase in blood pressure in response to high dietary salt intake,
is an independent risk factor for cardiovascular disease and mortality. It is associated with …