The cross-talk between LncRNAs and JAK-STAT signaling pathway in cancer

A Hjazi, RF Obaid, SS Ali, B Abdullaev… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) are non-coding RNAs that were transcribed from the
human genome and have become important regulators in a number of cellular activities …

Long non-coding RNAs and JAK/STAT signaling pathway regulation in colorectal cancer development

A Ghasemian, HA Omear, Y Mansoori… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the main fatal cancers. Cell signaling such as Janus
kinase/signal transducer and activator of transcription (JAK/STAT) signaling substantially …

[HTML][HTML] LncRNA-miRNA axis in tumor progression and therapy response: An emphasis on molecular interactions and therapeutic interventions

M Entezari, A Taheriazam, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …

LINC00669 insulates the JAK/STAT suppressor SOCS1 to promote nasopharyngeal cancer cell proliferation and invasion

X Qing, G Tan, H Liu, W Li, J Ai, S Xiong… - Journal of Experimental …, 2020 - Springer
Nasopharyngeal carcinoma (NPC) is an epithelial cancer emerging from the lining of
nasopharyngeal mucosa, with extremely frequent occurrence in east and southeast Asia …

Role of cytoplasmic lncRNAs in regulating cancer signaling pathways

P Fu, X Zheng, X Fan, A Lin - Journal of Zhejiang University-SCIENCE B, 2019 - Springer
Cancer remains a serious healthcare problem despite significant improvements in early
detection and treatment approaches in the past few decades. Novel biomarkers for …

The application of lncRNAs in cancer treatment and diagnosis

Y Zhang, L Tang - Recent patents on anti-cancer drug …, 2018 - ingentaconnect.com
Background: It is increasingly evident that lncRNAs have various biological functions playing
as essential regulators, getting involved in diverse cellular processes. Many of the lncRNAs …

Long non-coding RNA RP11-468E2. 5 curtails colorectal cancer cell proliferation and stimulates apoptosis via the JAK/STAT signaling pathway by targeting STAT5 …

L Jiang, XH Zhao, YL Mao, JF Wang, HJ Zheng… - Journal of Experimental …, 2019 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are tumor-associated biological
molecules and have been found to be implicated in the progression of colorectal cancer …

[HTML][HTML] The emerging role of major regulatory RNAs in cancer control

X Dai, AC Kaushik, J Zhang - Frontiers in oncology, 2019 - frontiersin.org
Alterations and personal variations of RNA interactions have been mechanistically coupled
with disease etiology and phenotypical variations. RNA biomarkers, RNA mimics, and RNA …

Interplay of miRNAs and lncRNAs in STAT3 signaling pathway in colorectal cancer progression

O Rahbar Farzam, S Najafi, M Amini, Z Rahimi… - Cancer Cell …, 2024 - Springer
In recent decades, colorectal cancer (CRC) has turned into one of the most widespread
malignancies, and the incidence of this malignancy is expected to increase. Despite …

LncRNA-mediated regulation of cell signaling in cancer

WX Peng, P Koirala, YY Mo - Oncogene, 2017 - nature.com
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …