Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity

C Konradt, CA Hunter - European journal of immunology, 2018 - Wiley Online Library
There are over 10 trillion endothelial cells (EC) that line the vasculature of the human body.
These cells not only have specialized functions in the maintenance of homeostasis within …

Vascular endothelial cells and innate immunity

Y Shao, J Saredy, WY Yang, Y Sun, Y Lu… - … , and vascular biology, 2020 - Am Heart Assoc
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

Endothelial cell infection and hemostasis

SK Sahni - Thrombosis research, 2007 - Elsevier
As an important component of the vasculature, endothelial cell lining covers the inner
surface of blood vessels and provides an active barrier interface between the vascular and …

Crossing the wall: the opening of endothelial cell junctions during infectious diseases

R Razakandrainibe, V Combes, GE Grau… - The international journal …, 2013 - Elsevier
Vascular endothelial cells (ECs) form a barrier that plays a crucial role in the health and
integrity of tissues by regulating the passage of molecules, liquids and immune cells …

The endothelium as a target for infections

G Valbuena, DH Walker - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
The endothelial cells lining vascular and lymphatic vessels are targets of several infectious
agents, including viruses and bacteria, that lead to dramatic changes in their functions …

Endothelial cells as innate immune cells

Y Lu, Y Sun, K Xu, Y Shao, F Saaoud… - Frontiers in …, 2022 - frontiersin.org
With the great effort and support from the authors and editorial team, our Research Topic
entitled “Endothelial cells as innate immune cells” in Frontiers in Immunology, Molecular …

Extra-and intracellular innate immune recognition in endothelial cells

B Opitz, S Hippenstiel, J Eitel… - Thrombosis and …, 2007 - thieme-connect.com
The innate immune system represents the principal sensor of infections in multicellular
organisms and might also mediate responses to some endogenous molecules. In this …

Innate immune recognition of lipopolysaccharide by endothelial cells

P Henneke, DT Golenbock - Critical care medicine, 2002 - journals.lww.com
Objective The endothelium is an active component of the innate immune response to
bacterial invasion. Endothelial cells comprise mechanisms to recognize structural patterns …

Interaction of pathogens with the endothelium

S Hippenstiel, N Suttorp - Thrombosis and Haemostasis, 2003 - thieme-connect.com
The endothelium lines the inner surface of the vessel wall establishing a multifunctional,
semi-permeable cellular barrier at blood-tissue interface. The large total surface of the …

Cytokine regulation of endothelial cell function: from molecular level to the bedside

A Mantovani, F Bussolino, M Introna - Immunology today, 1997 - cell.com
Endothelial cells (ECs) participate in inflammatory and immune reactions by producing and
responding to cytokines. The molecular basis underlying the functional reprograming of …