Metabolic syndrome (MetS) is a complicated health problem that encompasses a variety of
metabolic disorders. In this study, we analyzed the relationship between the major …

Background MicroRNAs play key roles in regulating cholesterol homeostasis. Here, we
investigated the role of microRNA-101 (miR-101) in regulating ATP-binding cassette …

ATP-binding cassette transporter A1 (ABCA1) plays a crucial role in reverse cholesterol
transport and exhibits anti-atherosclerosis effects. Some microRNAs (miRs) regulate ABCA1 …

Rationale Macrophage accumulation of cholesterol leads to foam cell formation which is a
major pathological event of atherosclerosis. Recent studies have shown that microRNA …

Background A high level of total cholesterol is associated with several lipid metabolism
disorders, including atherosclerosis and cardiovascular diseases. ATP-binding cassette …

Objective—The ATP-binding cassette transporter A1 (ABCA1) is a major regulator of
macrophage cholesterol efflux and protects cells from excess intracellular cholesterol …

There is emerging evidence identifying microRNAs (miRNAs) as mediators of statin-induced
cholesterol efflux, notably through the ATP-binding cassette transporter A1 (ABCA1) in …

Purpose Cholesterol efflux from macrophages to HDL, measured in vitro, is augmented by
treatment with agents which raise HDL cholesterol. In vitro, cholesterol depletion by statins is …

MicroRNAs (miRNAs, miRs) are small (18–25 nucleotides) noncoding RNAs that modulate
gene expression. Emerging evidence suggests that miRs are major regulators of lipoprotein …

Aim: ATP-binding cassette (ABC) transporters and endonuclease-exonuclease-
phosphatase family domain containing 1 (EEPD1) are reported to regulate cellular …