Connexin43 (Cx43) is commonly associated with direct cell–cell communication through
gap junctions (GJs). However, recent groundbreaking studies have challenged this dogma …

Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …

Connexins are assembled into dodecamer intercellular channels, a collection of which is
termed a gap junction, and their canonical function allowing direct exchange of ions and …

Simple Summary Connexin43 is one of the 21 members of a large protein family that forms
intercellular gap junction complexes. It plays a critical role in development by allowing two …

Connexin 43 (Cx43) is most widely distributed in mammals, especially in the cardiovascular
and nervous systems. Its phosphorylation state has been found to be regulated by the action …

Classically associated with gap junction-mediated intercellular communication, connexin43
(Cx43) is increasingly recognized to possess non-canonical biological functions, including …

Gap junctions are specialized cell–cell contacts that provide direct intercellular
communication between eukaryotic cells. The tyrosine-sorting signal (YXXØ), present at …

Connexins are integral membrane building blocks that form gap junctions, enabling direct
cytoplasmic exchange of ions and low-molecular-mass metabolites between adjacent cells …

Abstract Purpose of Review Considerable progress has been made in the field of stem cell
research; nonetheless, the use of stem cells for regenerative medicine therapies, for either …

Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …