The androgen receptor (AR) plays a predominant role in prostate cancer (PCa) pathology. It
consists of an N-terminal domain (NTD), a DNA-binding domain (DBD), a hinge region (HR) …

Androgens and androgen receptors (AR) play a pivotal role in expression of the male
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate …

Prostate cancer (PCa) accounted for over 300 000 deaths world-wide in 2018. Most of the
PCa deaths occurred due to the aggressive castration-resistant PCa (CRPC). Since the …

Androgen receptor (AR) is a transcription factor that becomes active upon binding to
androgens via its ligand-binding domain (LBD) or in response to signaling cascades …

The androgen receptor (AR) is dominant in prostate cancer (PCa) pathology. Current
therapeutic agents for advanced PCa include androgen synthesis inhibitors and AR …

The androgen receptor (AR) is a nuclear receptor transcription factor that mediates the
cellular actions of androgens, the male sex steroids. Androgen-dependent tissues, such as …

Prostate cancer (PCa) is the second most common cause of cancer‐related mortality in men
in the United States. The androgen receptor (AR) and the physiological pathways it …

Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and
dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding …

The androgen receptor (AR) plays an essential role in the growth and progression of
prostate cancer (CaP). Ligand-activated AR inside the nucleus binds to the androgen …

Introduction: Androgen receptor (AR) is a ligand-dependent transcription factor and a
member of the nuclear receptor superfamily. It plays a vital role in male sexual development …