MicroRNAs as therapeutics for future drug delivery systems in treatment of lung diseases

K Dua, NG Hansbro, PS Foster, PM Hansbro - Drug delivery and …, 2017 - Springer
The rapid advancement in the area of microRNAs (miRNAs) from discovery to their
translation into therapeutic moieties reflects their significance as important regulators in the …

MicroRNAs in lung diseases: recent findings and their pathophysiological implications

A Ebrahimi, E Sadroddiny - Pulmonary pharmacology & therapeutics, 2015 - Elsevier
Lung diseases are one of the leading causes of mortality and morbidity worldwide and
effective therapies are imperfect. Nonetheless, recently some novel strategies have been …

[HTML][HTML] MicroRNAs as therapeutic targets in lung disease: prospects and challenges

T Sato, H Baskoro, SI Rennard, K Seyama… - Chronic Obstructive …, 2016 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs that regulate multiple target genes
providing fine-tuned coordinated expression. Growing evidence suggests that miRNAs play …

The roles of miRNAs as potential biomarkers in lung diseases

SD Alipoor, IM Adcock, J Garssen, E Mortaz… - European journal of …, 2016 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs which can act as master regulators of
gene expression, modulate almost all biological process and are essential for maintaining …

[HTML][HTML] A perspective to weaponize microRNAs against lung cancer

D Murugan, L Rangasamy - Non-coding RNA Research, 2023 - Elsevier
Abstract microRNAs are regulatory RNAs that silence specific mRNA by binding to it,
inducing translational repression. Over the recent decades since the discovery of RNA …

MicroRNAs in lung diseases

G Hoefel, H Tay, P Foster - Chest, 2019 - Elsevier
Chronic inflammatory diseases of the lung are often life-threatening and are a leading cause
of morbidity in our communities. MicroRNAs (miRs) are now recognized to play critical roles …

Therapeutic use of microRNAs in lung cancer

O Fortunato, M Boeri, C Verri, M Moro… - BioMed research …, 2014 - Wiley Online Library
Lung cancer is a leading cause of cancer deaths worldwide. Although the molecular
pathways of lung cancer have been partly known, the high mortality rate is not markedly …

miRNA nanotherapeutics: potential and challenges in respiratory disorders

M Mehta, DK Chellappan, PR Wich… - Future medicinal …, 2020 - Taylor & Francis
Conclusion The expanded and in-depth research in understanding the roles of miRNA
opens up new possibilities for pulmonary disorders. The blend of miRNA with …

[HTML][HTML] Targeting microRNA function in respiratory diseases: mini-review

S Maltby, M Plank, HL Tay, A Collison… - Frontiers in …, 2016 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNA molecules that modulate expression of the
majority of genes by inhibiting protein translation. Growing literature has identified functional …

Role of microRNAs in lung development and pulmonary diseases

R Sessa, A Hata - Pulmonary circulation, 2013 - journals.sagepub.com
MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …