The latest advances concerning drug design and chemotherapy development to combat the
Chagas' disease are discussed. This chapter is based on the metabolic differences between …

Chagas disease or American Trypanosomiasis, a parasitic infection typically spread by
triatomine bugs, affects millions of people throughout Latin America. Current chemotherapy …

Chagas disease or American trypanosomiasis is considered by the Word Health
Organization to be one of the important tropical parasitic diseases worldwide together with …

Chagas disease, also known as American trypanosomiasis, is caused by infection with the
protozoan parasite Trypanosoma cruzi. The Pan American Health Organization (PAHO) …

Over the last two decades, progress towards new drugs for the treatment of Chagas' disease
has been disappointing. However, as a result of the parasite genome sequencing projects …

Human American trypanosomiasis, commonly called Chagas disease, is one of the most
neglected illnesses in the world and remains one of the most prevalent chronic infectious …

Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. It is a significant public health problem, affecting millions of people …

The review presents: a) a brief description of the disease; b) a summary of the most
important metabolic targets so far identified in Trypanosome cruzi (T. cruzi) along with …

American Trypanosomiasis, a parasitic infection commonly named Chagas disease, affects
millions of people all over Latin American countries. Presently, the World Health …

In this article we review the current status of chemotherapeutic approaches for the specific
treatment of Chagas disease or American Trypanosomiasis, as well as new rational …