Preventing acute kidney injury through nephrotoxin management

MA Perazella, FP Wilson - Nature Reviews Nephrology, 2016 - nature.com
Nephrotoxin-induced acute kidney injury (AKI) is a considerable risk among hospitalized
children. The development and use of a proactive, nephrotoxin screening system seems to …

Nephrotoxins and nephrotoxic acute kidney injury

AM Uber, SM Sutherland - Pediatric Nephrology, 2020 - Springer
Although the concept of nephrotoxicity has been recognized for more than 80 years, interest
in nephrotoxins has intensified dramatically over the past two decades. Much of this …

Administrative data misclassifies and fails to identify nephrotoxin-associated acute kidney injury in hospitalized children

JK Schaffzin, CN Dodd, H Nguyen… - Hospital …, 2014 - publications.aap.org
Objectives: Nephrotoxin exposure is a common cause of acute kidney injury (AKI) in
hospitalized children. AKI detection relies on regular serum creatinine (SCr) screening …

Nephrotoxin‐Related Acute Kidney Injury and Predicting High‐Risk Medication Combinations in the Hospitalized Child

KE Yonekawa, C Zhou, WL Haaland… - Journal of Hospital …, 2019 - Wiley Online Library
BACKGROUND In the hospitalized patient, nephrotoxin exposure is one potentially
modifiable risk factor for acute kidney injury (AKI). Clinical decision support based on …

Electronic health record identification of nephrotoxin exposure and associated acute kidney injury

SL Goldstein, E Kirkendall, H Nguyen, JK Schaffzin… - …, 2013 - publications.aap.org
BACKGROUND AND OBJECTIVE: Nephrotoxic medication exposure represents a common
cause of acute kidney injury (nephrotoxin-AKI) in hospitalized children. Systematic serum …

Nephrotoxin exposure and acute kidney injury in adults

BR Griffin, L Wendt, M Vaughan-Sarrazin… - Clinical journal of the …, 2023 - journals.lww.com
Background Rates of nephrotoxic AKI are not well described in adults due to lack of a clear
definition, debate over which drugs should be considered nephrotoxins, and illness-related …

System-Based Solutions to Minimizing Nephrotoxin-Induced Acute Kidney Injury

MT James, S Sawhney - Clinical Journal of the American Society …, 2023 - journals.lww.com
Drug-associated AKI is a common cause of iatrogenic AKI in hospitalized patients. 1 Drugs
can cause AKI via a variety of mechanisms, including parenchymal damage to the kidneys …

Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery

AM Uber, ME Montez-Rath, DM Kwiatkowski… - Pediatric …, 2018 - Springer
Background Though acute kidney injury (AKI) is often multifactorial, investigators are now
emphasizing the specific contribution of nephrotoxins. This study examines the …

[HTML][HTML] A sustained quality improvement program reduces nephrotoxic medication-associated acute kidney injury

SL Goldstein, T Mottes, K Simpson, C Barclay… - Kidney international, 2016 - Elsevier
Exposure to nephrotoxic medication is among the most common causes of acute kidney
injury (AKI) in hospitalized patients. Here we conducted a prospective quality improvement …

Toxin-related acute kidney injury

P Albuquerque, G Meneses - Nephrology and Public Health Worldwide, 2021 - karger.com
Clinical Background: Nephrotoxic acute kidney injury or toxin-related acute kidney injury
(ToxAKI) is a relevant and relatively common category of kidney damage. Exogenous toxins …