Drug delivery of cisplatin to breast cancer by polybutylcyanoacrylate nanoparticles

M Koohi Moftakhari Esfahani, SE Alavi… - Advances in Polymer …, 2018 - Wiley Online Library
Breast cancer is the most common cancer and the second cause of cancer‐related death in
women worldwide. Chemotherapy of disease is impeded by subsequent relapse and …

Investigating the properties and cytotoxicity of cisplatin-loaded nano-polybutylcyanoacrylate on breast cancer cells

A Gorgzadeh, A Hheidari, P Ghanbarikondori… - Asian Pacific Journal of …, 2023 - waocp.com
Background: This study aimed to develop a novel drug formulation using
polybutylcyanoacrylate (PBCA) nanoparticles to deliver cisplatin, a commonly used …

Poly (alkyl cyanoacrylate) nanoparticles for delivery of anti-cancer drugs

RSR Murthy, LH Reddy - Nanotechnology for cancer therapy, 2006 - taylorfrancis.com
Poly (alkyl cyanoacrylates) with a higher alkyl chain length is relatively less toxic than those
with a lower alkyl chain length. Several interesting studies were reported on the usefulness …

Enhancing anti-cancer efficacy of carboplatin by PEGylated poly (butyl cyanoacrylate) nano-particles

M Hassanzadeganroudsari, A Heydarinasab… - Journal of Drug Delivery …, 2019 - Elsevier
Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly (butylcyanoacrylate) nanoparticles

L Cabeza, R Ortiz, JL Arias, J Prados… - International journal …, 2015 - Taylor & Francis
The use of doxorubicin (DOX), one of the most effective antitumor molecules in the treatment
of metastatic breast cancer, is limited by its low tumor selectivity and its severe side effects …

Biodistribution of poly (alkyl cyanoacrylate) nanoparticles in mice and effect on tumor infiltration of macrophages into a patient-derived breast cancer xenograft

AD Pandya, TG Iversen, S Moestue, MT Grinde… - Nanomaterials, 2021 - mdpi.com
We have investigated the biodistribution and tumor macrophage infiltration after intravenous
injection of the poly (alkyl cyanoacrylate) nanoparticles (NPs): PEBCA (poly (2-ethyl-butyl …

Cisplatin encapsulated nanoparticles from polymer blends for anti-cancer drug delivery

KS Joshy, R Augustine, A Hasan, AA Zahid… - New Journal of …, 2022 - pubs.rsc.org
Developing novel nanocarriers for anticancer drug delivery has become a 'promising niche'.
The toxicity of the carrier and its efficacy in treatment modalities have become cardinal …

Cisplatin-loaded polybutylcyanoacrylate nanoparticles with improved properties as an anticancer agent

SE Alavi, S Muflih Al Harthi… - International Journal of …, 2019 - mdpi.com
This study aims to improve the cytotoxicity and potency of cisplatin-loaded
polybutylcyanoacrylate (PBCA) nanoparticles (NPs) for the treatment of lung cancer through …

Efficacy of Cisplatin-loaded polybutyl cyanoacrylate nanoparticles on the glioblastoma

H Ebrahimi Shahmabadi, F Movahedi… - Tumor Biology, 2014 - Springer
Glioblastoma is known as one of the most aggressive human cancers. To gain access of the
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …

Nanoparticles as microcarriers for anticancer drugs

P Couvreur, L Roblot-Treupel, MF Poupon… - Advanced Drug Delivery …, 1990 - Elsevier
This paper surveys the current status of anticancer drug delivery by means of
polyalkylcyanoacrylate nanoparticles. In spite of the development of numerous …