[HTML][HTML] Connectivity and functionality of the globus pallidus externa under normal conditions and Parkinson's disease

J Dong, S Hawes, J Wu, W Le, H Cai - Frontiers in neural circuits, 2021 - frontiersin.org
The globus pallidus externa (GPe) functions as a central hub in the basal ganglia for
processing motor and non-motor information through the creation of complex connections …

The external globus pallidus: progress and perspectives

DJ Hegeman, ES Hong… - European Journal of …, 2016 - Wiley Online Library
The external globus pallidus (GP e) of the basal ganglia is in a unique and powerful position
to influence processing of motor information by virtue of its widespread projections to all …

Functional connectivity and integrative properties of globus pallidus neurons

D Jaeger, H Kita - Neuroscience, 2011 - Elsevier
The globus pallidus consists of the external (GPe) and the internal (GPi) segments. The GPe
and GPi have different functional roles. The GPe is located centrally within multiple basal …

Parvalbumin+ and Npas1+ pallidal neurons have distinct circuit topology and function

A Pamukcu, Q Cui, HS Xenias, BL Berceau… - Journal of …, 2020 - Soc Neuroscience
The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. Phasic
changes in the activity of GPe neurons during movement and their alterations in …

Parvalbumin+ neurons and Npas1+ neurons are distinct neuron classes in the mouse external globus pallidus

VM Hernández, DJ Hegeman, Q Cui… - Journal of …, 2015 - Soc Neuroscience
Compelling evidence suggests that pathological activity of the external globus pallidus
(GPe), a nucleus in the basal ganglia, contributes to the motor symptoms of a variety of …

New roles for the external globus pallidus in basal ganglia circuits and behavior

AH Gittis, JD Berke, MD Bevan, CS Chan… - Journal of …, 2014 - Soc Neuroscience
The development of methodology to identify specific cell populations and circuits within the
basal ganglia is rapidly transforming our ability to understand the function of this complex …

[HTML][HTML] Synchrony in Parkinson's disease: importance of intrinsic properties of the external globus pallidus

BC Schwab, T Heida, Y Zhao, E Marani… - Frontiers in systems …, 2013 - frontiersin.org
The mechanisms for the emergence and transmission of synchronized oscillations in
Parkinson's disease, which are potentially causal to motor deficits, remain debated. Aside …

Dysregulation of external globus pallidus‐subthalamic nucleus network dynamics in parkinsonian mice during cortical slow‐wave activity and activation

RF Kovaleski, JW Callahan, M Chazalon… - The Journal of …, 2020 - Wiley Online Library
Key points Reciprocally connected GABAergic external globus pallidus (GPe) and
glutamatergic subthalamic nucleus (STN) neurons form a key network within the basal …

[HTML][HTML] Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a …

J Liu, GP Shelkar, LP Sarode, DY Gawande… - Neurobiology of …, 2021 - Elsevier
Globus pallidus externa (GPe) is a nucleus in the basal ganglia circuitry involved in the
control of movement. Recent studies have demonstrated a critical role of GPe cell types in …

Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits

V Lilascharoen, EHJ Wang, N Do, SC Pate… - Nature …, 2021 - nature.com
The basal ganglia regulate a wide range of behaviors, including motor control and cognitive
functions, and are profoundly affected in Parkinson's disease (PD). However, the functional …