[HTML][HTML] Connectivity and functionality of the globus pallidus externa under normal conditions and Parkinson's disease
The globus pallidus externa (GPe) functions as a central hub in the basal ganglia for
processing motor and non-motor information through the creation of complex connections …
processing motor and non-motor information through the creation of complex connections …
The external globus pallidus: progress and perspectives
DJ Hegeman, ES Hong… - European Journal of …, 2016 - Wiley Online Library
The external globus pallidus (GP e) of the basal ganglia is in a unique and powerful position
to influence processing of motor information by virtue of its widespread projections to all …
to influence processing of motor information by virtue of its widespread projections to all …
Functional connectivity and integrative properties of globus pallidus neurons
D Jaeger, H Kita - Neuroscience, 2011 - Elsevier
The globus pallidus consists of the external (GPe) and the internal (GPi) segments. The GPe
and GPi have different functional roles. The GPe is located centrally within multiple basal …
and GPi have different functional roles. The GPe is located centrally within multiple basal …
Parvalbumin+ and Npas1+ pallidal neurons have distinct circuit topology and function
The external globus pallidus (GPe) is a critical node within the basal ganglia circuit. Phasic
changes in the activity of GPe neurons during movement and their alterations in …
changes in the activity of GPe neurons during movement and their alterations in …
Parvalbumin+ neurons and Npas1+ neurons are distinct neuron classes in the mouse external globus pallidus
VM Hernández, DJ Hegeman, Q Cui… - Journal of …, 2015 - Soc Neuroscience
Compelling evidence suggests that pathological activity of the external globus pallidus
(GPe), a nucleus in the basal ganglia, contributes to the motor symptoms of a variety of …
(GPe), a nucleus in the basal ganglia, contributes to the motor symptoms of a variety of …
New roles for the external globus pallidus in basal ganglia circuits and behavior
The development of methodology to identify specific cell populations and circuits within the
basal ganglia is rapidly transforming our ability to understand the function of this complex …
basal ganglia is rapidly transforming our ability to understand the function of this complex …
[HTML][HTML] Synchrony in Parkinson's disease: importance of intrinsic properties of the external globus pallidus
The mechanisms for the emergence and transmission of synchronized oscillations in
Parkinson's disease, which are potentially causal to motor deficits, remain debated. Aside …
Parkinson's disease, which are potentially causal to motor deficits, remain debated. Aside …
Dysregulation of external globus pallidus‐subthalamic nucleus network dynamics in parkinsonian mice during cortical slow‐wave activity and activation
RF Kovaleski, JW Callahan, M Chazalon… - The Journal of …, 2020 - Wiley Online Library
Key points Reciprocally connected GABAergic external globus pallidus (GPe) and
glutamatergic subthalamic nucleus (STN) neurons form a key network within the basal …
glutamatergic subthalamic nucleus (STN) neurons form a key network within the basal …
[HTML][HTML] Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a …
Globus pallidus externa (GPe) is a nucleus in the basal ganglia circuitry involved in the
control of movement. Recent studies have demonstrated a critical role of GPe cell types in …
control of movement. Recent studies have demonstrated a critical role of GPe cell types in …
Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits
V Lilascharoen, EHJ Wang, N Do, SC Pate… - Nature …, 2021 - nature.com
The basal ganglia regulate a wide range of behaviors, including motor control and cognitive
functions, and are profoundly affected in Parkinson's disease (PD). However, the functional …
functions, and are profoundly affected in Parkinson's disease (PD). However, the functional …