Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

JA Dani, D Bertrand - Annu. Rev. Pharmacol. Toxicol., 2007 - annualreviews.org
Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from
numerous subunit combinations that compose channel-receptor complexes with varied …

Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies

DC Perry, MI Dávila-Garcı́a, CA Stockmeier… - Journal of Pharmacology …, 1999 - ASPET
Chronic administration of nicotine increases the density of neuronal cholinergic nicotinic
receptors in cells and in rodent brain, and similar increases have been reported in brains …

Neuronal nicotinic receptors: from structure to function

S Leonard, D Bertrand - Nicotine & Tobacco Research, 2001 - academic.oup.com
Molecular identification of the genes and resulting protein sequences for a large number of
nicotinic acetylcholine receptor (nAChR) subunits has stimulated numerous studies …

Neuronal nicotinic receptors and synaptic transmission in the mammalian central nervous system

EX Albuquerque, EFR Pereira, M Alkondon… - Neuronal Nicotinic …, 2000 - Springer
Although the psychopharmacological effects of nicotine have been known since the last
century, it was not until the end of the 1980s that neuronal nicotinic acetylcholine receptors …

Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H] cytisine

HK Happe, JL Peters, DA Bergman, LC Murrin - Neuroscience, 1994 - Elsevier
There is a great deal of interest in the role of nicotinic acetylcholine receptors in the central
nervous system, although their function is not well understood at present. Currently, central …

Nicotinic acetylcholine receptor subtypes in human frontal cortex: changes in Alzheimer's disease

K Sugaya, E Giacobini… - Journal of neuroscience …, 1990 - Wiley Online Library
Molecular genetic and pharmacological studies have suggested that several subtypes of
nicotinic acetylcholine receptors exist in the mammalian and avian brain. Combining 3H‐(−) …

Human brain nicotinic receptors, their distribution and participation in neuropsychiatric disorders

AJ Graham, CM Martin-Ruiz… - Current Drug Targets …, 2002 - ingentaconnect.com
Mapping of nicotinic acetylcholine receptor (nAChR) subtypes and subunits in human brain
is far from complete, however it is clear that multiple subunits are present (including α3, α4 …

Distribution of nicotinic receptors in the human hippocampus and thalamus

F Rubboli, JA Court, C Sala, C Morris… - European Journal of …, 1994 - Wiley Online Library
Neuronal nicotinic acetylcholine receptors consist of different subunits, α and β, with different
subtype arrangement corresponding to distinct pharmacological and functional properties …

Nicotine and brain disorders.

S Mihailescu, R Drucker-Colin - Acta Pharmacologica Sinica, 2000 - europepmc.org
During the last decade, brain nicotinic acetylcholine receptors were extensively
characterized from electrophysiological and pharmacological points of view. These …

Neuronal nicotinic acetylcholine receptor structure and function and response to nicotine

JA Dani - International review of neurobiology, 2015 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) belong to the “Cys-loop” superfamily of ligand-
gated ion channels that includes GABA A, glycine, and serotonin (5-HT 3) receptors. There …