Global analysis of immune evasion strategies in Staphylococcus aureus clinical isolates

T Brignoli - 2019 - amsdottorato.unibo.it
Staphylococcus aureus is a major human pathogen, leading cause of soft tissue and blood
stream infections. One of the causes of its success as a pathogen is the peculiar array of …

[HTML][HTML] Absence of protein a expression is associated with higher capsule production in staphylococcal isolates

T Brignoli, AGO Manetti, R Rosini, AF Haag… - Frontiers in …, 2019 - frontiersin.org
Staphylococcus aureus is a major human pathogen, and a leading cause of soft tissue and
blood stream infections. One of the causes of its success as a pathogen is the peculiar array …

[HTML][HTML] The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine development

A Bear, T Locke, S Rowland-Jones… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
While Staphylococcus aureus (S. aureus) bacteria are part of the human commensal flora,
opportunistic invasion following breach of the epithelial layers can lead to a wide array of …

[HTML][HTML] A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia

AK Varshney, GA Kuzmicheva, J Lin, KM Sunley… - PLoS …, 2018 - journals.plos.org
Staphylococcus aureus can cause devastating and life-threatening infections. With the
increase in multidrug resistant strains, novel therapies are needed. Limited success with …

[HTML][HTML] Natural human immunity against staphylococcal protein A relies on effector functions triggered by IgG3

E Boero, AR Cruz, W Pansegrau, C Giovani… - Frontiers in …, 2022 - frontiersin.org
Staphylococcal protein A (SpA) is a multifunctional, highly conserved virulence factor of
Staphylococcus aureus. By binding the Fc portion of all human IgG subclasses apart from …

Staphylococcus aureus adaptation to the host and persistence: role of loss of capsular polysaccharide expression

L Tuchscherr, B Löffler, FR Buzzola… - Future …, 2010 - Future Medicine
A vast array of virulence factors enable Staphylococcus aureus to readily adapt to different
environmental niches in diverse hosts. The cap gene cluster is present in almost all relevant …

Recurrent infections and immune evasion strategies of Staphylococcus aureus

HK Kim, V Thammavongsa, O Schneewind… - Current opinion in …, 2012 - Elsevier
Staphylococcus aureus causes purulent skin and soft tissue infections (SSTIs) that
frequently reoccur. Staphylococal SSTIs can lead to invasive disease and sepsis, which are …

Staphylococcus aureus Pathogenesis Based on Genetic Background

Y Sato'o - … aureus: Interplay between Bacteria and Hosts, 2024 - Springer
Staphylococcus aureus is a common pathogen. Although it is always present in or near
humans and animals, it can sometimes unleash its pathogenic potential and lead to …

Staphylococcus aureus protein A promotes immune suppression

SD Kobayashi, FR DeLeo - MBio, 2013 - Am Soc Microbiol
Staphylococcus aureus is a prominent cause of human infections worldwide and is
notorious for its ability to acquire resistance to antibiotics. Methicillin-resistant S. aureus …

[HTML][HTML] Genetic variation in Staphylococcus aureus surface and immune evasion genes is lineage associated: implications for vaccine design and host-pathogen …

AJ McCarthy, JA Lindsay - BMC microbiology, 2010 - Springer
Background S. aureus is a coloniser and pathogen of humans and mammals. Whole
genome sequences of 58 strains of S. aureus in the public domain and data from multi-strain …