Spatiotemporal changes in diffusion, T2 and susceptibility of white matter following mild traumatic brain injury

W Li, JA Long, L Watts, Q Shen, Y Liu… - NMR in …, 2016 - Wiley Online Library
Impaired white matter integrity in traumatic brain injury (TBI) can lead to deficits in various
neurological functions. The differentiation of the underlying pathological processes, eg …

Imaging markers for the characterization of gray and white matter changes from acute to chronic stages after experimental traumatic brain injury

MRT Sinke, WM Otte, AE Meerwaldt… - Journal of …, 2021 - liebertpub.com
Despite clinical symptoms, a large majority of people with mild traumatic brain injury (TBI)
have normal computed tomography (CT) and magnetic resonance imaging (MRI) scans …

Alterations in microstructure and local fiber orientation of white matter are associated with outcome after mild traumatic brain injury

M Mohammadian, T Roine, J Hirvonen… - Journal of …, 2020 - liebertpub.com
Mild traumatic brain injury (mTBI) can have long-lasting consequences. We investigated
white matter (WM) alterations at 6–12 months following mTBI using diffusion tensor imaging …

Multiparametric and longitudinal MRI characterization of mild traumatic brain injury in rats

JA Long, LT Watts, J Chemello, S Huang… - Journal of …, 2015 - liebertpub.com
This study reports T2 and diffusion-tensor magnetic resonance imaging (MRI) studies of a
mild open-skull, controlled cortical impact injury in rats (n= 6) from 3 h to up to 14 d after …

White matter tract integrity: an indicator of axonal pathology after mild traumatic brain injury

S Chung, E Fieremans, X Wang… - Journal of …, 2018 - liebertpub.com
We seek to elucidate the underlying pathophysiology of injury sustained after mild traumatic
brain injury (mTBI) using multi-shell diffusion magnetic resonance imaging, deriving …

Combined diffusion tensor imaging and quantitative susceptibility mapping discern discrete facets of white matter pathology post-injury in the rodent brain

N Soni, V Vegh, XV To, AZ Mohamed, K Borges… - Frontiers in …, 2020 - frontiersin.org
Early loss of white matter microstructure integrity is a significant cause of long-term
neurological disorders following traumatic brain injury (TBI). White matter abnormalities …

Increase in apparent diffusion coefficient in normal appearing white matter following human traumatic brain injury correlates with injury severity

P Goetz, A Blamire, B Rajagopalan… - Journal of …, 2004 - liebertpub.com
Following diffuse traumatic brain injury, there may be persistent functional or psychological
deficits despite the presence of normal conventional MR images. Previous experimental …

Acute white matter tract damage after frontal mild traumatic brain injury

JJ Herrera, K Bockhorst, S Kondraganti… - Journal of …, 2017 - liebertpub.com
Our understanding of mild traumatic brain injury (mTBI) is still in its infancy and to gain a
greater understanding, relevant animal models should replicate many of the features seen in …

Serial changes in the white matter diffusion tensor imaging metrics in moderate traumatic brain injury and correlation with neuro-cognitive function

R Kumar, M Husain, RK Gupta, KM Hasan… - Journal of …, 2009 - liebertpub.com
Diffuse axonal injury (DAI) that follows traumatic brain injury (TBI) is thought to be a major
contributor to neurocognitive dysfunction that sometimes follows TBI. Conventional magnetic …

White matter microstructure in chronic moderate‐to‐severe traumatic brain injury: Impact of acute‐phase injury‐related variables and associations with outcome …

AK Håberg, A Olsen, KG Moen… - Journal of …, 2015 - Wiley Online Library
This study examines how injury mechanisms and early neuroimaging and clinical measures
impact white matter (WM) fractional anisotropy (FA), mean diffusivity (MD), and tract volumes …