High-sugar, but not high-fat, food activates supraoptic nucleus neurons in the male rat
C Hume, N Sabatier, J Menzies - Endocrinology, 2017 - academic.oup.com
Oxytocin is a potent anorexigen and is believed to have a role in satiety signaling. We
developed rat models to study the activity of oxytocin neurons in response to voluntary …
developed rat models to study the activity of oxytocin neurons in response to voluntary …
Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats
JM Ho, VT Anekonda, BW Thompson, M Zhu… - …, 2014 - academic.oup.com
Oxytocin (OT)-elicited hypophagia has been linked to neural activity in the nucleus of the
solitary tract (NTS). Because plasma OT levels increase after a meal, we hypothesized that …
solitary tract (NTS). Because plasma OT levels increase after a meal, we hypothesized that …
The “metabolic sensor” function of rat supraoptic oxytocin and vasopressin neurons is attenuated during lactation but not in diet-induced obesity
CD Sladek, W Stevens, Z Song… - American Journal …, 2016 - journals.physiology.org
The oxytocin (OT) and vasopressin (VP) neurons of the supraoptic nucleus (SON)
demonstrate characteristics of “metabolic sensors”. They express insulin receptors and …
demonstrate characteristics of “metabolic sensors”. They express insulin receptors and …
Molecular, immunohistochemical, and pharmacological evidence of oxytocin's role as inhibitor of carbohydrate but not fat intake
PK Olszewski, A Klockars, AM Olszewska… - …, 2010 - academic.oup.com
Oxytocin (OT) facilitates feeding termination stemming from high osmolality, stomach
distention, and malaise. Recent knockout (KO) studies suggested a crucial function for OT in …
distention, and malaise. Recent knockout (KO) studies suggested a crucial function for OT in …
Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin
A Mitra, BA Gosnell, HB Schiöth, MK Grace, A Klockars… - Peptides, 2010 - Elsevier
Increased tone of orexigens mediating reward occurs upon repeated consumption of sweet
foods. Interestingly, some of these reward orexigens, such as opioids, diminish activity of …
foods. Interestingly, some of these reward orexigens, such as opioids, diminish activity of …
Relay of peripheral oxytocin to central oxytocin neurons via vagal afferents for regulating feeding
Y Iwasaki, P Kumari, L Wang, S Hidema… - Biochemical and …, 2019 - Elsevier
Oxytocin (Oxt), a neurohormone synthesized in the neurons of hypothalamic paraventricular
nucleus (PVN) and supraoptic nucleus induces milk-ejection and uterine contraction and …
nucleus (PVN) and supraoptic nucleus induces milk-ejection and uterine contraction and …
Peripheral oxytocin activates vagal afferent neurons to suppress feeding in normal and leptin-resistant mice: a route for ameliorating hyperphagia and obesity
Y Iwasaki, Y Maejima, S Suyama… - American journal …, 2015 - journals.physiology.org
Oxytocin (Oxt), a neuropeptide produced in the hypothalamus, is implicated in regulation of
feeding. Recent studies have shown that peripheral administration of Oxt suppresses …
feeding. Recent studies have shown that peripheral administration of Oxt suppresses …
A new oxytocin-saporin cytotoxin for lesioning oxytocin-receptive neurons in the rat hindbrain
DG Baskin, F Kim, RW Gelling, BJ Russell… - …, 2010 - academic.oup.com
Evidence suggests that release of oxytocin in the nucleus tractus solitarius (NTS) of the
hindbrain from descending projections that originate in the paraventricular nucleus can …
hindbrain from descending projections that originate in the paraventricular nucleus can …
Oxytocin, feeding, and satiety
N Sabatier, G Leng, J Menzies - Frontiers in endocrinology, 2013 - frontiersin.org
Oxytocin neurons have a physiological role in food intake and energy balance. Central
administration of oxytocin is powerfully anorexigenic, reducing food intake and meal …
administration of oxytocin is powerfully anorexigenic, reducing food intake and meal …
Oxytocin and food intake control: Neural, behavioral, and signaling mechanisms
The neuropeptide oxytocin is produced in the paraventricular hypothalamic nucleus and the
supraoptic nucleus of the hypothalamus. In addition to its extensively studied influence on …
supraoptic nucleus of the hypothalamus. In addition to its extensively studied influence on …