Load and lock: the molecular mechanisms of B‐lymphocyte commitment
The maturation of B‐lymphoid cells from hematopoietic stem cells in the bone marrow is a
complex process under control of interplay between extrinsic and intrinsic factors. In addition …
complex process under control of interplay between extrinsic and intrinsic factors. In addition …
Role of transcription factors in commitment and differentiation of early B lymphoid cells
S Roessler, R Grosschedl - Seminars in immunology, 2006 - Elsevier
B lymphopoiesis is a differentiation process in which hematopoietic stem cells are converted
into antibody-producing plasma cells. B cell differentiation involves multiple steps, including …
into antibody-producing plasma cells. B cell differentiation involves multiple steps, including …
B-cell commitment: deciding on the players
RR Hardy - Current opinion in immunology, 2003 - Elsevier
Considerable progress has been made over the past few years in determining the key
molecular players that regulate the commitment and development of early B-lineage cells in …
molecular players that regulate the commitment and development of early B-lineage cells in …
Molecular regulation of differentiation in early B-lymphocyte development
M Sigvardsson - International journal of molecular sciences, 2018 - mdpi.com
B-lymphocyte differentiation is one of the best understood developmental pathways in the
hematopoietic system. Our understanding of the developmental trajectories linking the …
hematopoietic system. Our understanding of the developmental trajectories linking the …
Transcriptional regulation of lymphocyte development
S Dias, W Xu, S McGregor, B Kee - Current opinion in genetics & …, 2008 - Elsevier
B lymphocytes and T lymphocytes develop from hematopoietic stem cells through a series of
intermediates with progressively decreased lineage differentiation potential. Differentiation …
intermediates with progressively decreased lineage differentiation potential. Differentiation …
Epigenetic events during B lymphocyte development
M Parra - Epigenetics, 2009 - Taylor & Francis
The generation of B cells is the result of several cell lineage choices, cell commitment and
differentiation. These cellular transitions take place in a stepwise manner and are regulated …
differentiation. These cellular transitions take place in a stepwise manner and are regulated …
B-lymphocyte commitment: identifying the point of no return
E Welinder, J Åhsberg, M Sigvardsson - Seminars in immunology, 2011 - Elsevier
Even though B-lymphocyte development is one of the best understood models for cell
differentiation in the hematopoetic system, recent advances in cell sorting and functional …
differentiation in the hematopoetic system, recent advances in cell sorting and functional …
Genetic networks that regulate B lymphopoiesis
KL Medina, H Singh - Current opinion in hematology, 2005 - journals.lww.com
Genetic networks that regulate B lymphopoiesis : Current Opinion in Hematology Genetic
networks that regulate B lymphopoiesis : Current Opinion in Hematology Log in or Register …
networks that regulate B lymphopoiesis : Current Opinion in Hematology Log in or Register …
Regulation of lineage commitment during lymphocyte development
FJT Staal, HC Clevers - International Reviews of Immunology, 2001 - Taylor & Francis
B and T lymphocytes develop from pluripotent hematopoietic stem cells through a complex
differentiation pathway involving many different phenotypically distinct subpopulations [11 …
differentiation pathway involving many different phenotypically distinct subpopulations [11 …
Complementary regulation of early B-lymphoid differentiation by genetic and epigenetic mechanisms
T Yokota, T Sudo, T Ishibashi, Y Doi, M Ichii… - International journal of …, 2013 - Springer
Although B lymphopoiesis is one of the best-defined paradigms in cell differentiation, our
knowledge of the regulatory mechanisms underlying its earliest processes, in which …
knowledge of the regulatory mechanisms underlying its earliest processes, in which …