Most messenger RNAs from eukaryotic cells terminate at the 3'end with a long stretch of
polyadenylic acid. Only one exception is known so far: histone mRNA. The questions raised …

Department of Biological Sciences, Columbia University, New York, NY 10027 mRNAs in
eukaryotic cells, as every fresh-man biology student of the last 20 or so years has learned …

The messenger RNA of Escherichia coli polyribosomes was analyzed by a variety of
methods for the presence of sequences of polyadenylic acid. No such sequences were …

Chinese hamster and mouse sarcoma 180 ascites cells, treated with high levels of
actinomycin D, still carry out limited poly (A) synthesis. The residual activity, which consists …

A structure consisting of poly (A) complexed with other components is released from
polysomes by ribonuclease treatment. The poly (A) complex has a sedimentation value of 12 …

IT is commonly assumed that the messenger RNA (mRNA) of prokaryotes lacks the poly (A)
sequences which characterise the 3′ terminus of most mRNA of eukaryotes. A report of the …

Publisher Summary This chapter describes that the poly (A) segment in mRNA provides a
dramatic example of an accessory polynucleotide sequence that is clearly not involved in …

It is now firmly established that most, but not all, eukaryotic mRNAs possess a poly (A)
sequence attached to the 3'end [1, 2]. The function of the poly (A) moiety, of mRNA is not …

The presence of polyadenylate sequences at the 3'-end of mRNA was first observed in
eukaryotic cells about 25 years ago (Darnel1 et al., 1971; Edmonds et al., 1971; Lee et al …

We had shown earlier (Gopalakrishna, Y., Langley, D., Sarkar, N.(1981) Nucleic Acid Res. 9,
3545-3554) that a substantial fraction of mRNA of various bacterial species carries 3' …