Cancer is the most challenging disease of our time with increasing numbers of new cases
each year, worldwide. Great achievements have been reached in cancer research through …

The introduction of targeted therapy is the biggest success in the treatment of cancer in the
past few decades. However, heterogeneous cancer is characterized by diverse molecular …

A breast cancer genome is a record of the historic mutagenic activity that has occurred
throughout the development of the tumor. Indeed, every mutation may be informative …

Breast cancer is the most common malignancy in women all over the world. Genetic
background of women contributes to her risk of having breast cancer. Certain inherited DNA …

The past decade has witnessed the cataloging of genetic mutations in cancer genomes,
providing new insights into how and in what ways cancer can develop and spread (1, 2) …

Cancer cells continue to challenge scientists and oncologists due to the phenomenon of
resistance. Moreover, recurrence, as seen in many treated patients, shows that currently …

Personalized cancer therapy is likely to be one of the next big advances in our search for a
cure for cancer. To be able to treat people in an individualized manner, researchers need to …

Signatures of DNA-Repair Deficiencies in Breast Cancer | NEJM Skip to main content NEJM
Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

Many cancers, including breast cancer, have demonstrated prognosis and support
advantages thanks to the discovery of targeted therapies. The advent of these new …

Somatic mutations developed with missense, silent, insertions and deletions have varying
effects on the resulting protein and are one of the important reasons for cancer development …