[HTML][HTML] The relationship between diabetes mellitus and gastric cancer and the potential benefits of metformin: an extensive review of the literature

CH Tseng - Biomolecules, 2021 - mdpi.com
The objective of this review is to summarize the findings of published research that
investigated the relationship between diabetes mellitus and gastric cancer (GCa) and the …

[HTML][HTML] Metformin use and its effect on gastric cancer in patients with type 2 diabetes: a systematic review of observational studies

P Li, C Zhang, P Gao, X Chen, B Ma… - Oncology …, 2018 - spandidos-publications.com
Increasing evidence suggests that metformin use is associated with a decreased risk of
cancer. The traditional therapies for gastric cancer (GC) are gastrectomy and …

[HTML][HTML] Association between metformin and the risk of gastric cancer in patients with type 2 diabetes mellitus: a meta-analysis of cohort studies

XL Zhou, WH Xue, XF Ding, LF Li, MM Dou, WJ Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Objectives The objective of this study was to evaluate the association between metformin
therapy and the incidence of gastric cancer (GC) in patients with type 2 diabetes mellitus …

Diabetes mellitus and gastric cancer: correlation and potential mechanisms

L Wang, Z Zhang - Journal of Diabetes Research, 2023 - Wiley Online Library
This review summarizes the correlation between diabetes mellitus (DM) and gastric cancer
(GC) from the perspectives of epidemiology, drug use, and potential mechanisms. The …

The effect of metformin on gastric cancer in patients with type 2 diabetes: a systematic review and meta-analysis

Y Shuai, C Li, X Zhou - Clinical and Translational Oncology, 2020 - Springer
Background Metformin, a drug widely used in the treatment of diabetes, has proven
preventive and survival benefits for various malignancies. However, the effect of metformin …

[HTML][HTML] Mechanism underlying metformin action and its potential to reduce gastric cancer risk

WH Lan, TY Lin, JA Yeh, CL Feng, JT Hsu… - International journal of …, 2022 - mdpi.com
Diabetes mellitus is associated with a high risk of developing gastric cancer (GC). Metformin,
which is conventionally used to treat type 2 diabetes, induces AMP-activated protein kinase …

[HTML][HTML] Metformin reduces gastric cancer risk in patients with type 2 diabetes mellitus

CH Tseng - Aging (Albany NY), 2016 - ncbi.nlm.nih.gov
This retrospective cohort study investigated whether metformin may reduce gastric cancer
risk by using the reimbursement databases of the Taiwan's National Health Insurance …

Effect of metformin use on survival and recurrence rate of gastric cancer after gastrectomy in diabetic patients: a systematic review and meta-analysis of observational …

M Bahardoust, S Mousavi, ZD Moezi, M Yarali… - Journal of …, 2024 - Springer
Background Gastric cancer (GC) is one of the most common worldwide cancers and causes
of death. Various studies have investigated the effect of metformin on overall survival (OS) …

[HTML][HTML] A cohort study of antihyperglycemic medication exposure and gastric cancer risk

A Dulskas, A Patasius, A Kaceniene… - Journal of clinical …, 2020 - mdpi.com
We assessed gastric cancer risk in type 2 diabetes mellitus patients. Gastric cancer patients
with diabetes between 2001–2012 were identified. Four groups were analysed: combination …

Relationship between diabetes and risk of gastric cancer: A systematic review and meta-analysis of cohort studies

J Guo, C Liu, J Pan, J Yang - Diabetes Research and Clinical Practice, 2022 - Elsevier
Patients with diabetes mellitus (DM) are at increased risk of developing several cancers;
however, there is a lack of consensus on the relationship between gastric cancer (GC) and …