The roles and role-players in thyroid cancer angiogenesis

S Rajabi, MH Dehghan, R Dastmalchi… - Endocrine …, 2019 - jstage.jst.go.jp
Thyroid cancer is the most prevalent endocrine cancer worldwide. Angiogenesis, the
formation of new blood vessels, plays a pivotal role in the development and progression of …

Prognostic and therapeutic role of angiogenic microenvironment in thyroid cancer

A Melaccio, LI Sgaramella, A Pasculli, G Di Meo… - Cancers, 2021 - mdpi.com
Simple Summary Angiogenesis is an essential event for the progression of solid tumors and
is promoted by angiogenic cytokines released in the tumor microenvironment by neoplastic …

Angiogenesis in benign and malignant thyroid disease

JC Mitchell, S Parangi - Thyroid, 2005 - liebertpub.com
Context Angiogenesis has been recognized as an important process contributing to the
pathophysiology of many benign and malignant diseases. It is not surprising, therefore, that …

Targeting vascular endothelial growth factor receptor in thyroid cancer: the intracellular and extracellular implications

SM Keefe, MA Cohen, MS Brose - Clinical Cancer Research, 2010 - AACR
Our understanding of the molecular pathophysiology of differentiated thyroid cancer (DTC)
has developed considerably over the last 10 years. Aberrant signaling through B-Raf and …

Molecular target based combinational therapeutic approaches in thyroid cancer

S Rajoria, R Suriano, AL George, A Kamat… - Journal of Translational …, 2012 - Springer
Background Thyroid cancer, as with other types of cancer, is dependent on angiogenesis for
its continued growth and development. Interestingly, estrogen has been shown to contribute …

VEGF in physiological process and thyroid disease

M Klein, B Catargi - Annales d'endocrinologie, 2007 - Elsevier
Angiogenesis is a physiological process involving the growth of new vessels from pre-
existing vasculature. Vascular endothelial growth factor (VEGF) is an important regulator of …

Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological features

G Bunone, P Vigneri, L Mariani, S Butó, P Collini… - The American journal of …, 1999 - Elsevier
Experimental evidence has shown, both in vitro and in animal models, that neoplastic
growth and subsequent metastasis formation depend on the tumor's ability to induce an …

Angiogenesis and lymphangiogenesis in thyroid proliferative lesions: relationship to type and tumour behaviour

NG de la Torre, I Buley, JAH Wass… - Endocrine-Related …, 2006 - erc.bioscientifica.com
The role of angiogenesis and lymphangiogenesis in thyroid cancer pathogenesis has not
been elucidated. Patterns for tumour behaviour and metastasic spread vary according to …

Aberrant thyroid-stimulating hormone receptor signaling increases VEGF-A and CXCL8 secretion of thyroid cancer cells, contributing to angiogenesis and tumor …

YS Song, MJ Kim, HJ Sun, HH Kim, HS Shin… - Clinical Cancer …, 2019 - AACR
Purpose: Thyroid-stimulating hormone (TSH) suppression is widely used to treat well-
differentiated thyroid cancer, whereas its role in poorly differentiated thyroid cancer (PDTC) …

Co-regulatory potential of vascular endothelial growth factor–A and vascular endothelial growth factor–C in thyroid carcinoma

A Salajegheh, S Pakneshan, A Rahman… - Human pathology, 2013 - Elsevier
Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels.
The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and …