Background Single-cell RNA-seq (scRNA-seq) is emerging as a powerful tool to dissect cell-
specific effects of drug treatment in complex tissues. This application requires high levels of …

The development of high-throughput single-cell RNA sequencing (scRNA-seq) has enabled
access to information about gene expression in individual cells and insights into new …

Background Single-cell RNA sequencing (scRNA-seq) provides valuable insights into
human islet cell types and their corresponding stable gene expression profiles. However …

Single-cell RNA sequencing (scRNA-seq) has significantly deepened our insights into
complex tissues, with the latest techniques capable of processing tens of thousands of cells …

Background Single-cell RNA sequencing (scRNA-Seq) is an increasingly popular platform
to study heterogeneity at the single-cell level. Computational methods to process scRNA …

Computational single-cell RNA-seq (scRNA-seq) methods have been successfully applied
to experiments representing a single condition, technology, or species to discover and …

Motivation Single-cell RNA sequencing (scRNA-seq) technology has revolutionized the way
research is done in biomedical sciences. It provides an unprecedented level of resolution …

Complex biological systems are composed of multiple cell types whose transcriptional
activity can vary due to differences in cell state, environmental stimulation, or intrinsic …

Single-cell RNA-seq (scRNA-seq) assays are being increasingly utilized to investigate
specific hypotheses in both basic biology and clinically-applied studies. The design of most …

Motivation Single-cell RNA-sequencing (scRNA-seq) allows whole transcriptome profiling of
thousands of individual cells, enabling the molecular exploration of tissues at the cellular …