A method for whole cell in situ hybridization in Paramecium was developed, which allowed
us to visualize both the cytoplasmic mRNA and the transcripts in the macronucleus, and to …

The effect of the microtubule inhibitor nocodazole was studied on Paramecium and shown to
arrest cell multiplication, depolymerize the internal microtubule network, and block the …

First discovered in the fungus Aspergillus nidulans [1], γ-tubulin is a ubiquitous component
of microtubule organizing centres [2]. In centrosomes, γ-tubulin has been immunolocalized …

Microtubules are highly dynamic protein polymers that and are essential for intracellular
organization and fundamental processes like transport and cell division. In cells, a wide …

Propofol belongs to a class of molecules that are known to block learning and memory in
mammals, including rodents and humans. Interestingly, learning and memory are not tied to …

Ciliates are highly differentiated cells which display extensive deployment of microtubular
systems. Because genetic diversity of tubulin is extremely reduced in these cells …

Microtubules in neurons consist of highly dynamic regions as well as stable regions, some of
which persist after bouts of severing as short mobile polymers. Concentrated at the plus …

For hundreds of millions of years, pancake-shaped animals about the size of a sharp pencil
tip have been roving the seas with an appetite for tasty microbes and algae. They're called …

Previous experiments have clearly demonstrated that microtubule dynamic instability is
regulated in living cells, but the molecular mechanisms that are responsible for this …

Despite a rapid turnover of subunits, how cells control the lengths of cytoskeletal filaments
(such as microtubules) is a fundamental question in cell biology. Here, we theoretically …