Oxidative damage and inflammation are related to the pathogenesis of age-related macular
degeneration (AMD). Epidemiologic studies suggest that insufficient dietary lutein and …

The degeneration of the retinal pigment epithelium caused by oxidative damage is a stage
of development in age-related macular degeneration (AMD). The carotenoid lutein is a …

Retinal pigment epithelial (RPE) cells are central to retinal health and homoeostasis.
Oxidative stress-induced damage to the RPE occurs as part of the pathogenesis of age …

Lutein and zeaxanthin, two carotenoid pigments of the xanthophyll subclass, are present in
high concentrations in the retina, especially in the macula. They work as a filter protecting …

Age-related macular degeneration, the leading cause of blindness in the elderly, is a
degenerative condition of the macula characterized by death or dysfunction of the …

The lens and retina of the human eye are exposed constantly to light and oxygen. In situ
phototransduction and oxidative phosphorylation within photoreceptors produces a high …

Purpose Epidemiological studies suggest that dietary intake of lutein and zeaxanthin is
inversely related to the risk for senile cataract. The objectives of this work were to investigate …

Epidemiological studies suggest that consumption of vegetables rich in the xanthophylls
lutein (LUT) and zeaxanthin (ZEA) reduces the risk for developing age-related cataract, a …

purpose. Oxidative stress has been proposed as a major pathogenic factor in age-related
macular degeneration (AMD), the leading cause of vision loss among elderly people of …

Lutein slows the progression of age-related macular degeneration (AMD), a leading cause
of blindness in ageing societies. However, the underlying mechanisms remain elusive …