[HTML][HTML] The role of xanthine oxidoreductase and uric acid in metabolic syndrome
Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …
through the oxidative stress and the inflammatory response induced by XOR-derived …
[HTML][HTML] Metabolic syndrome and cancer risk: the role of xanthine oxidoreductase
Obesity and related pathologies such as diabetes and metabolic syndrome are associated
with chronic inflammation and cancer. The serum level of xanthine oxidoreductase (XOR) is …
with chronic inflammation and cancer. The serum level of xanthine oxidoreductase (XOR) is …
[HTML][HTML] Xanthine oxidoreductase: A leading actor in cardiovascular disease drama
Cardiovascular diseases (CVD) are the leading cause of global mortality and their
pathogenesis lies mainly in the atherosclerotic process. There are close connections linking …
pathogenesis lies mainly in the atherosclerotic process. There are close connections linking …
[HTML][HTML] Xanthine oxidoreductase in atherosclerosis pathogenesis: Not only oxidative stress
MG Battelli, L Polito, A Bolognesi - Atherosclerosis, 2014 - Elsevier
Endothelial xanthine oxidoreductase (XOR) together with NAD (P) H oxidase and nitric
oxide (NO) synthase plays a physiologic role in inflammatory signalling, the regulation of NO …
oxide (NO) synthase plays a physiologic role in inflammatory signalling, the regulation of NO …
New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity
M Furuhashi - American Journal of Physiology …, 2020 - journals.physiology.org
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …
Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications
CE Berry, JM Hare - The Journal of physiology, 2004 - Wiley Online Library
There is substantial evidence that oxidative stress participates in the pathophysiology of
cardiovascular disease. Biochemical, molecular and pharmacological studies further …
cardiovascular disease. Biochemical, molecular and pharmacological studies further …
The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors
N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …
[HTML][HTML] Xanthine oxidoreductase: One enzyme for multiple physiological tasks
Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from
a complicated evolutionary process that assigned it many physiological roles. The main …
a complicated evolutionary process that assigned it many physiological roles. The main …
Plasma xanthine oxidoreductase activity as a novel biomarker of metabolic disorders in a general population
M Furuhashi, M Matsumoto, M Tanaka, N Moniwa… - Circulation …, 2018 - jstage.jst.go.jp
Background: Xanthine oxidoreductase (XOR) is an enzyme that catalyzes the formation of
uric acid from hypoxanthine and xanthine, leading to an increase in superoxide and reactive …
uric acid from hypoxanthine and xanthine, leading to an increase in superoxide and reactive …
Uric acid as one of the important factors in multifactorial disorders–facts and controversies
D Pasalic, N Marinkovic, L Feher-Turkovic - Biochemia medica, 2012 - hrcak.srce.hr
Sažetak With considering serum concentration of the uric acid in humans we are observing
hyperuricemia and possible gout development. Many epidemiological studies have shown …
hyperuricemia and possible gout development. Many epidemiological studies have shown …