Cognitive impairment and dementia are significant health burdens worldwide. Aging,
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …

Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

Background: Cerebral small vessel disease (cSVD), a common risk factor for cognitive
impairment, involves unspecific arteriopathy characterized by hypertrophy and endothelial …

Cerebral small vessel disease (CSVD) is one of the most important causes of vascular
dementia. Immunosenescence and inflammatory response, with the involvement of the …

Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Vascular dementia is the second-most cause of dementia, characterized by cerebral infarcts,
white matter lesions, myelin loss and often amyloid angiopathy. Hence, vascular damage is …

The prevalence of dementia is increasing in our aging population at an alarming rate.
Because of the heterogeneity of clinical presentation and complexity of disease …

As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

Vascular pathology of the brain is the second most common cause of cognitive impairment
after Alzheimer's disease. The article describes the modern concepts of etiology …

Vascular dementia (VD), a cerebrovascular disease which causes cognitive impairment, is
one of the significant factors that affects the quality of senectitude. Atherosclerosis (AS) is a …