Biological risk factors influencing vascular cognitive impairments: a review of the evidence

S Iluț, ŞC Vesa, V Văcăraș, L Brăiță, VC Dăscălescu… - Brain Sciences, 2023 - mdpi.com
Vascular cognitive impairment encompasses several types of deficits, ranging from mild
cognitive impairment to dementia. Cognitive reserve refers to the brain's ability to balance …

[HTML][HTML] Diagnosis and treatment of vascular damage in dementia

GJ Biessels - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
This paper provides an overview of cognitive impairment due to vascular brain damage,
which is referred to as vascular cognitive impairment (VCI). Over the past decades, we have …

[HTML][HTML] Aging and cerebrovascular health: Structural, functional, cognitive, and methodological implications

M Fabiani, B Rypma, G Gratton - Psychophysiology, 2021 - ncbi.nlm.nih.gov
Aging is often accompanied by declines in a range of cognitive domains, including fluid
intelligence (Baltes, Dittmann-Kohli, & Kliegl, 1986; Park & Reuter-Lorenz, 2009), speed of …

Cerebrovascular structure and dementia: new drug targets

J Atkinson - Trends in Pharmacological Sciences, 2001 - cell.com
Effective pharmacological treatment of cognitive disorders in dementia is lacking despite
extensive efforts to produce active therapy aimed at neuronal and vascular targets. In this …

[PDF][PDF] Vascular and nonvascular mechanisms of cognitive impairment and dementia

B Kara, MN Gordon, M Gifani, AM Dorrance… - Clinics in geriatric …, 2023 - Elsevier
Aging, familial gene mutations, and genetic, environmental, and modifiable lifestyle risk
factors predispose individuals to cognitive impairment or dementia by influencing the …

Metabolic syndrome and vascular-associated cognitive impairment: a focus on preclinical investigations

TA Jenkins - Current Diabetes Reports, 2022 - Springer
Abstract Purpose of Review Metabolic syndrome is associated with an increased risk of
vascular cognitive impairment or, in the more extreme, vascular dementia. Animal models …

Rethinking Vascular Dementia (Part 2 of 2)

T Erkinjuntti, VC Hachinski - Cerebrovascular Diseases, 1993 - karger.com
Vascular dementia is growing in importance, so is the confusion surrounding it. Vascular
dementia may be regarded as a syndrome of cognitive impairment resulting from vascular …

Vascular cognitive impairment and dementia: An early career researcher perspective

NCBS Silva, O Bracko, AR Nelson… - … & disease monitoring, 2022 - Wiley Online Library
The field of vascular contributions to cognitive impairment and dementia (VCID) is evolving
rapidly. Research in VCID encompasses topics aiming to understand, prevent, and treat the …

Experimental models of vascular dementia and vascular cognitive impairment: a systematic review

NS Jiwa, P Garrard… - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 814–828. Abstract Vascular cognitive impairment (VCI)
encompasses vascular dementia and is the second most common cause of dementing …

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease

A Csiszar, S Tarantini, GA Fülöp, T Kiss… - Geroscience, 2017 - Springer
Hypertension in the elderly substantially increases both the risk of vascular cognitive
impairment (VCI) and Alzheimer's disease (AD); however, the underlying mechanisms are …