Synaptic basal lamina such as laminin‐421 (α4β2γ1) mediate differentiation of the
neuromuscular junction (NMJ). Laminins interact with their pre‐or postsynaptic receptors to …

Laminin-α4 is involved in the alignment of active zones to postjunctional folds at the
neuromuscular junction (NMJ). Prior study has implicated laminin-α4 in NMJ maintenance …

A prominent feature of synaptic maturation at the neuromuscular junction (NMJ) is the
topological transformation of the acetylcholine receptor (AChR)-rich postsynaptic membrane …

The synapse between motor neurons and skeletal muscle is known as the neuromuscular
junction (NMJ). Proper alignment of presynaptic and post-synaptic structures of motor …

Laminin is a major component of all basement membranes. However, its composition varies
with location because there are numerous forms of each of the three chains (α, β, and γ) that …

Laminins, heterotrimers of α, β, and γ chains, are prominent constituents of basal laminae
(BLs) throughout the body. Previous studies have shown that laminins affect both …

Nerve regeneration studies at the neuromuscular junction (NMJ) suggest that synaptic basal
lamina components tell the returning axon where to locate neurotransmitter release …

Precise apposition of pre-to postsynaptic specializations is required for optimal function of
chemical synapses, but little is known about how it is achieved. At the skeletal …

The vertebrate neuromuscular junction (NMJ) remains the best‐studied model for
understanding the mechanisms involved in synaptogenesis, due to its relatively large size …

Laminin α2-deficient congenital muscular dystrophy is a debilitating disease affecting both
muscle and neural tissue as a result of mutations in the LAMA2 gene. It presents at or soon …