Expression of human interferon-γ by Bombyx mori baculovirus expression system and detection of antiviral activity of the product.

Z Zeng, J Li, X Liu, P Tang, Y Li, Z Zhang, X Shen, Y Yi - 2021 - cabidigitallibrary.org
Abstract Interferon-γ (IFN-γ) is an important immunomodulatory factor in immune response,
which can activate a variety of immune cells. In this study, silkworm baculovirus expression …

Efficient production of canine interferon-alpha in silkworm Bombyx mori by use of a BmNPV/Bac-to-Bac expression system

Z Na, Y Huipeng, L Lipan, C Cuiping… - Applied microbiology …, 2008 - Springer
We exploited the silkworm Bombyx mori for the production of recombinant canine interferon-
alpha (CaIFN-α). The recombinant baculovirus harboring canine interferon gene was rapidly …

High-level expression of human beta-interferon gene in the silkworm with new constructed BmNPV vector.

J Deng, S Wang, Q Yang, X Cheng… - Chinese Journal of …, 1995 - europepmc.org
Bombyx mori nuclear polyhedrosis virus (BmNPV) and Bombyx mori cells as well as
silkworm larvae were used successfully for the production of biologically active recombinant …

High-level Expression of the Human-α-interferon Gene through the Use of an Improved Baculovirus Vector in the Silkworm, Bombyx mori

T Horiuchi, Y Marumoto, Y Saeki, Y Sato… - Agricultural and …, 1987 - academic.oup.com
During research on the production of human α-interferon (α-IFN) in silkworms using a
baculovirus, Bombyx mori nuclear polyhedrosis virus (BmNPV), as a vector, the expression …

Molecular cloning of feline interferon cDNA by direct expression and its mass production using silkworm

N Nakamura, T Sudo, Y Ueda, T Sakurai… - … Engineering for 2001 …, 1992 - Springer
Interferon (IFN) is biological substance showing antiviral activity, whose main ingredient is
protein. Many mammalian IFNs have been reported, and some human IFNs (HuIFNs) are …

Production of biologically active recombinant bovine interferon-γ by two different baculovirus gene expression systems using insect cells and silkworm larvae

K Murakami, A Uchiyama, T Kokuho, Y Mori, H Sentsui… - Cytokine, 2001 - Elsevier
The full-length bovine interferon-γ (bIFN-γ) cDNA, including the secretion signal peptide
coding region was recloned into baculovirus transfer vectors pAcYM1 and pBm050. These …

Expression of Sheep Interferon Alpha in Silkworm and Determination of Its Activity Against Peste Des Petits Ruminants Virus

D LI, XIU DU Meng-tan, X LIU… - Biotechnology …, 2022 - biotech.aiijournal.com
Interferon has broad-spectrum anti-viral and anti-tumor activities and can enhance the
body's anti-viral ability, thus interferon has been widely used in the prevention and control of …

Expression of bovine interferon gamma in recombinant baculovirus and determination of its antiviral activity

LT Qin, XJ Wang, S Hu, SD Liu, ZG Bu - Wei Sheng wu xue bao …, 2007 - europepmc.org
The full-length bovine interferon gamma (BoIFN-gamma) cDNA, including the secretion
signal peptide coding region was recloned into baculovirus honor vectors pFastBac 1 of Bac …

Production of canine IFN-γ in silkworm by recombinant baculovirus and characterization of the product

F Okano, M Satoh, T Ido, N Okamoto… - Journal of Interferon & …, 2000 - liebertpub.com
Canine interferon-γ (CaIFN-γ) cDNA was expressed in silkworm by infecting recombinant
baculovirus. Western blot analyses revealed that the resulting preparation contained various …

Expression of recombinant human interferon-γ with antiviral activity in the bi-cistronic baculovirus-insect/larval system

WS Chen, OB Villaflores, TR Jinn… - Bioscience …, 2011 - academic.oup.com
A bi-cistronic baculovirus-insect/larval system containing a polyhedron promoter, an internal
ribosome entry site (IRES), and an egfp gene was developed as a cost-effective platform for …