The role of platelets in atherosclerotic process and subsequently in the pathophysiology of
cardiovascular disease is essential as platelets in addition to their contribution to thrombosis …

Platelets are small, anucleate blood elements of critical importance in cardiovascular
disease. The ability of platelets to activate and aggregate to form blood clots in response to …

Platelets play important roles in thrombosis-dependent obstructive cardiovascular diseases.
In addition, it has now become evident that platelets also participate in the earliest stages of …

Platelets are blood cell fragments that originate from the cytoplasm of megakaryocytes in the
bone marrow and circulate in blood to play a major role in the hemostatic process and in …

Beyond their role in hemostasis and thrombosis platelets are critically involved in the onset
of atherosclerosis. Platelets represent an important linkage between inflammation, and …

Platelet functions are multiple, complex and not limited to haemostasis. In fact, platelets play
a relevant role in vascular inflammation and atherosclerosis (ATS). In the presence of …

The physiopathology of atherothrombosis is complex. The development and progression of
this vascular disease involves the interactive processes of atherosclerotic lesions and the …

The functional interplay of platelets with leukocytes and endothelial cells is critical both in
physiological conditions, such as host defense, wound repair and tissue healing, and in …

iN bRieF Page 1 www.nature.com/nrcardio A new study identifies the genetic locus encoding the
histone deacety l ase HDAC9 as a risk locus associated with calcification of the abdomi nal aorta …

Review on platelet function in inflammation and atherosclerosis. Platelets play a crucial role
in the physiology of the primary hemostasis and in the pathophysiological activity of arterial …