Tissue non-specific alkaline phosphatase and vascular calcification: a potential therapeutic target

D Azpiazu, S Gonzalo… - Current cardiology …, 2019 - ingentaconnect.com
Vascular calcification is a pathologic phenomenon consisting of calcium phosphate crystal
deposition in the vascular walls. Vascular calcification has been found to be a risk factor for …

An update on vascular calcification and potential therapeutics

A Singh, S Tandon, C Tandon - Molecular Biology Reports, 2021 - Springer
Pathological calcification is a major cause of cardiovascular morbidities primarily in
population with chronic kidney disease (CKD), end stage renal diseases (ERSD) and …

Vascular calcification: pathobiological mechanisms and clinical implications

RC Johnson, JA Leopold, J Loscalzo - Circulation research, 2006 - Am Heart Assoc
Once thought to result from passive precipitation of calcium and phosphate, it now appears
that vascular calcification is a consequence of tightly regulated processes that culminate in …

Vascular calcification mechanisms: updates and renewed insight into signaling pathways involved in high phosphate-mediated vascular smooth muscle cell …

N Abbasian - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is associated with aging, cardiovascular and renal diseases and
results in poor morbidity and increased mortality. VC occurs in patients with chronic kidney …

Regulatory mechanisms in vascular calcification

K Bostrom, LL Demer - Critical Reviews™ in Eukaryotic Gene …, 2000 - dl.begellhouse.com
Regulatory Mechanisms in Page 1 Critical ili’evi'ewsTM in Eukaryotic Gene Expression, l2(2):l5l—!58
(2000) Regulatory Mechanisms in Vascular Calcification Kristina Bostr6m* and Linda L. Demer …

Calcium signaling and tissue calcification

D Proudfoot - Cold Spring Harbor Perspectives in …, 2019 - cshperspectives.cshlp.org
Calcification is a regulated physiological process occurring in bones and teeth. However,
calcification is commonly found in soft tissues in association with aging and in a variety of …

The molecular biology and pathophysiology of vascular calcification

MF McCarty, JJ DiNicolantonio - Postgraduate medicine, 2014 - Taylor & Francis
Vascular calcification (VC), commonly encountered in renal failure, diabetes, and aging, is
associated with a large increase in the risk for cardiovascular events and mortality …

Mechanisms of vascular calcification in kidney disease

S Disthabanchong, P Srisuwarn - Advances in chronic kidney disease, 2019 - Elsevier
The increase in prevalence and severity of vascular calcification in chronic kidney disease is
a result of complex interactions between changes in the vascular bed, mineral metabolites …

Mechanisms and clinical consequences of vascular calcification

D Zhu, NCW Mackenzie, C Farquharson… - Frontiers in …, 2012 - frontiersin.org
Vascular calcification has severe clinical consequences and is considered an accurate
predictor of future adverse cardiovascular events, including myocardial infarction and stroke …

[HTML][HTML] Recent progress in the treatment of vascular calcification

WC O'neill, KA Lomashvili - Kidney international, 2010 - Elsevier
Vascular calcification is common in patients with advanced chronic kidney disease and is
associated with poorer outcomes. Although the pathophysiology is not completely …