[HTML][HTML] Impaired CD8+ T cell responses upon Toll-like receptor activation in common variable immunodeficiency

C de Lollo, D de Moraes Vasconcelos… - Journal of translational …, 2016 - Springer
Background Infections caused by bacteria or viruses are frequent in common variable
immunodeficiency (CVID) patients due to antibody deficiencies, which may be associated …

Chemokine, cytokine and type I interferon production induced by Toll-like receptor activation in common variable immune deficiency

C de Lollo, D de Moraes Vasconcelos… - Clinical …, 2016 - Elsevier
Common variable immunodeficiency (CVID) is the most common symptomatic primary
antibody deficiency and is associated with recurrent infections and chronic inflammatory …

The role of toll-like receptors in B-cell development and immunopathogenesis of common variable immunodeficiency

L Sharifi, A Mirshafiey, N Rezaei, G Azizi… - Expert review of …, 2016 - Taylor & Francis
Common variable immunodeficiency (CVID) is the most frequent symptomatic primary
immune deficiency and is characterized by hypogammaglobulinemia, defect in specific …

Toll-like receptor 7 and 9 defects in common variable immunodeficiency

EY Joyce, AK Knight, L Radigan, TU Marron… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Common variable immunodeficiency (CVID) is characterized by
hypogammaglobulinemia, reduced numbers of peripheral blood isotype-switched memory B …

[HTML][HTML] Chronically activated T-cells retain their inflammatory properties in common variable immunodeficiency

RM Berbers, MM van der Wal, JM van Montfrans… - Journal of Clinical …, 2021 - Springer
Purpose Immune dysregulation complications cause significant morbidity and mortality in
common variable immunodeficiency (CVID), but the underlying pathophysiology is poorly …

Toll-like receptors pathway in common variable immune deficiency (CVID) and X-linked agammaglobulinemia (XLA)

P Tavasolian, L Sharifi, A Aghamohammadi… - European Cytokine …, 2018 - Springer
Common variable immunodeficiency (CVID) and X-linked agammaglobulinemia (XLA) are
two major humoral immunodeficiencies, causing a high rate of early age mortality in …

[PDF][PDF] 7 Quantitative and Functional Evaluation of Innate Immune Responses in Patients With Common Variable Immunodeficiency

CM Trujillo, C Muskus, J Arango… - Journal of …, 2011 - esmonformacion.com
■ Abstract Objectives: We evaluate the frequency and functional response of innate
immune cells in peripheral blood (PB) from patients with common variable …

Preferential reduction of circulating innate lymphoid cells type 2 in patients with common variable immunodeficiency with secondary complications is part of a broader …

D Friedmann, B Keller, I Harder, J Schupp… - Journal of Clinical …, 2017 - Springer
Purpose Over a third of patients with common variable immunodeficiency (CVID) suffer from
secondary complications like inflammatory organ disease, autoimmune manifestations, or …

The profile of toll-like receptor 2 (TLR2), TLR4 and their cytosolic downstream signaling pathway in common variable immunodeficiency (CVID) patients

L Sharifi, A Aghamohammadi, N Rezaei… - Iranian Journal of …, 2018 - ijaai.tums.ac.ir
Common variable immunodeficiency (CVID) is the most common clinical primary antibody
deficiency, characterized by increased susceptibility to recurrent bacterial infections. Since …

Reduced numbers of circulating group 2 innate lymphoid cells in patients with common variable immunodeficiency

CB Geier, S Kraupp, D Bra, MM Eibl… - European journal of …, 2017 - Wiley Online Library
Recent studies identified an emerging role of group 2 and 3 innate lymphoid cells (ILCs) as
key players in the generation of T‐dependent and T‐independent antibody production. In …