[HTML][HTML] Serum sphingolipid profiling as a novel biomarker for metabolic syndrome characterization

L Berkowitz, C Salazar, CD Ryff, CL Coe… - Frontiers in …, 2022 - frontiersin.org
Background Sphingolipids are components of cell membrane structure, but also circulate in
serum and are essential mediators of many cellular functions. While ceramides have been …

[HTML][HTML] Dietary fat and protein intake in relation to plasma sphingolipids as determined by a large-scale lipidomic analysis

JYH Seah, WS Chew, F Torta, CM Khoo, MR Wenk… - Metabolites, 2021 - mdpi.com
Sphingolipid concentrations have been associated with risk of type 2 diabetes and
cardiovascular diseases. Because sphingolipids can be synthesized de novo from saturated …

[图书][B] Sphingolipids as signaling and regulatory molecules

C Chalfant, M Del Poeta - 2011 - books.google.com
This book attempts to analyze the latest discoveries in sphingolipid biology and how the
alteration of their metabolism leads to altered signaling events and to the development of …

A simple and rapid method for extraction and measurement of circulating sphingolipids using LC–MS/MS: a targeted lipidomic analysis

Y Xu, H Li, Y Han, T Wang, Y Wang, J Gong… - Analytical and …, 2022 - Springer
Sphingolipids are a class of lipids with high structural diversity and biological pleiotropy.
Mounting evidence supports a role for sphingolipids in regulating pathophysiology of …

[HTML][HTML] Sphingolipids in obesity and related complications

KM Boini, S Koka, M Xia, JK Ritter… - Frontiers in bioscience …, 2017 - ncbi.nlm.nih.gov
Sphingolipids, ubiquitously produced in all vertebrate cells, are biologically active lipids that
are the structural components of cell membranes. They also function as intracellular and …

[HTML][HTML] Phospholipids and sphingolipids in nutrition, metabolism, and health

R Lordan, CN Blesso - Frontiers in Nutrition, 2023 - frontiersin.org
Phospholipids and sphingolipids are ubiquitous in nature. Often referred to as polar lipids,
these lipids are essential components in cell membranes and consist of a hydrophilic head …

Sphingolipids in food and their critical roles in human health

X Wang, Y Wang, J Xu, C Xue - Critical Reviews in Food Science …, 2021 - Taylor & Francis
Sphingolipids (SLs) are ubiquitous structural components of cell membranes and are
essential for cell functions under physiological conditions or during disease progression …

Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis

JYH Seah, WS Chew, F Torta, CM Khoo, MR Wenk… - Metabolomics, 2020 - Springer
Introduction Sphingolipids are a diverse class of lipids with various roles in cell functions
and subclasses such as ceramides have been associated with cardiovascular diseases …

Sphingolipid metabolism and analysis in metabolic disease

SE Brice, LA Cowart - Sphingolipids and Metabolic Disease, 2011 - Springer
Sphingolipids are an important class of structural and signaling molecules within the cell. As
sphingolipids have been implicated in the development and pathogenesis of insulin …

[HTML][HTML] Altered sphingoid base profiles in type 1 compared to type 2 diabetes

N Wei, J Pan, R Pop-Busui, A Othman, I Alecu… - Lipids in health and …, 2014 - Springer
Background Sphingolipids are increasingly recognized to play a role in insulin resistance
and diabetes. Recently we reported significant elevations of 1-deoxysphingolipids (1 …