Chemical insights into the issues of Gd retention in the brain and other tissues upon the administration of Gd‐containing MRI contrast agents
Gadolinium bearing contrast agents (GBCA) are commonly used in clinical settings as they
add relevant physiological information to the superb anatomical resolution of the MR …
add relevant physiological information to the superb anatomical resolution of the MR …
The biological fate of gadolinium-based MRI contrast agents: a call to action for bioinorganic chemists
Gadolinium-based contrast agents (GBCAs) are widely used with clinical magnetic
resonance imaging (MRI), and 10 s of millions of doses of GBCAs are administered annually …
resonance imaging (MRI), and 10 s of millions of doses of GBCAs are administered annually …
Quantification and assessment of the chemical form of residual gadolinium in the brain after repeated administration of gadolinium-based contrast agents: comparative …
T Frenzel, C Apte, G Jost, L Schöckel… - Investigative …, 2017 - journals.lww.com
Objective Multiple clinical and preclinical studies have reported a signal intensity increase
and the presence of gadolinium (Gd) in the brain after repeated administration of Gd-based …
and the presence of gadolinium (Gd) in the brain after repeated administration of Gd-based …
Spatially resolved quantification of gadolinium deposited in the brain of a patient treated with gadolinium-based contrast agents
S Fingerhut, AC Niehoff, M Sperling, A Jeibmann… - Journal of Trace …, 2018 - Elsevier
Due to its paramagnetic properties resulting from seven unpaired f-electrons, Gd is
frequently applied in magnetic resonance imaging examinations. Due to the acute toxicity of …
frequently applied in magnetic resonance imaging examinations. Due to the acute toxicity of …
Speciation analysis of gadolinium in the water-insoluble rat brain fraction after administration of gadolinium-based contrast agents
I Strzeminska, C Factor, P Robert, J Szpunar… - Investigative …, 2021 - journals.lww.com
Purpose To date, the analysis of gadolinium (Gd) speciation in the brain of animals
administered with macrocyclic and linear Gd-based contrast agents (GBCAs) has been …
administered with macrocyclic and linear Gd-based contrast agents (GBCAs) has been …
Long-term evaluation of gadolinium retention in rat brain after single injection of a clinically relevant dose of gadolinium-based contrast agents
I Strzeminska, C Factor, P Robert, AL Grindel… - Investigative …, 2020 - journals.lww.com
Purpose The aim of this study was to investigate the presence and chemical forms of
residual gadolinium (Gd) in rat brain after a single dose of Gd-based contrast agent …
residual gadolinium (Gd) in rat brain after a single dose of Gd-based contrast agent …
Distribution and chemical forms of gadolinium in the brain: a review
T Kanda, Y Nakai, A Hagiwara, H Oba… - The British journal of …, 2017 - academic.oup.com
In the 3 years since residual gadolinium-based contrast agent (GBCA) in the brain was first
reported, much has been learned about its accumulation, including the pathway of GBCA …
reported, much has been learned about its accumulation, including the pathway of GBCA …
Gadolinium retention in the rat brain: assessment of the amounts of insoluble gadolinium-containing species and intact gadolinium complexes after repeated …
E Gianolio, P Bardini, F Arena, R Stefania… - Radiology, 2017 - pubs.rsna.org
Purpose To evaluate the speciation of gadolinium-containing species after multiple
administrations of the gadolinium-based contrast agents (GBCAs) gadodiamide and …
administrations of the gadolinium-based contrast agents (GBCAs) gadodiamide and …
[HTML][HTML] Gadolinium deposition in the brain: another concern regarding gadolinium-based contrast agents
N Karabulut - Diagnostic and Interventional Radiology, 2015 - ncbi.nlm.nih.gov
Life is continuously confronting us with new issues and sometimes breaking our rou-tine.
One case in point is the curious way radiologists' knowledge about the benefits and risks of …
One case in point is the curious way radiologists' knowledge about the benefits and risks of …
Gadolinium in medical imaging—usefulness, toxic reactions and possible countermeasures—A review
L Blomqvist, GF Nordberg, VM Nurchi, JO Aaseth - Biomolecules, 2022 - mdpi.com
Gadolinium (Gd) is one of the rare-earth elements. The properties of its trivalent cation
(Gd3+) make it suitable to serve as the central ion in chelates administered intravenously to …
(Gd3+) make it suitable to serve as the central ion in chelates administered intravenously to …